HER3, a member of the EGFR family of receptor tyrosine kinases coded by the ERBB3 gene,
plays an important role in cancer, despite its lack of intrinsic kinase activity. As with genes …

It is well established that the epidermal growth factor (EGF) receptor, receptor tyrosine-
protein kinase erbB-2 (ERBB2)/human EGF receptor 2 (HER2), and, to a lesser extent …

Objective Mucinous ovarian carcinoma (MOC) is an uncommon ovarian cancer histotype
that responds poorly to conventional chemotherapy regimens. Although long overall survival …

Prostate cancer (PCa) is associated with a high incidence and metastasis rate globally,
resulting in an unsatisfactory prognosis and a huge economic burden due to the current …

The human epidermal growth factor receptor (HER) family consists of four transmembrane
receptor tyrosine kinases: epidermal growth factor receptor (EGFR), HER2, HER3, and …

Colorectal carcinomas that are mismatch repair (MMR)‐deficient in the absence of MLH1
promoter methylation or germline mutations represent Lynch‐like syndrome (LLS). Double …

ABSTRACT A number of treatments have been developed for HER1, 2 and 3-driven non-
small cell lung cancer (NSCLC), of which the most successful have been the epidermal …

Dihydromethysticin (DHM), a natural compound derived from Kava, has been reported to be
effective against mental disorders and some malignant tumors. However, little is known …

Recently, a large number of studies found that activation of ERBB3 (Erb-B2 receptor tyrosine
kinase 3, also known as HER3) may be one of the major mechanisms underlying resistance …

Lung cancer is the commonest cause of cancer deaths worldwide. Although strongly
associated with smoking, predisposition to lung cancer is also heritable, with multiple …