Chromatin remodeling complexes (CRCs) use ATP hydrolysis to maintain correct
expression profiles, chromatin stability, and inherited epigenetic states. More than 20 CRCs …

The largest subtype of breast cancer is characterized by the expression and activity of the
estrogen receptor alpha (ERalpha/ER). Although several effective therapies have …

Emerging research on epigenetics has resulted in many novel discoveries in atherosclerosis
(AS), an inflammaging-associated disease characterized by chronic inflammation primarily …

Ovarian cancer (OC) is the fifth leading cause of women's death from cancers. The high
mortality rate is attributed to the late presence of the disease and the lack of modern …

Epigenetics, one mechanism by which gene expression can change without any changes to
the DNA sequence, was described nearly a century ago. However, the importance of …

The CCCTC-binding factor (CTCF) organises the genome in 3D through DNA loops and in
1D by setting boundaries isolating different chromatin states, but these processes are not …

Cell lineage specification is a tightly regulated process that is dependent on appropriate
expression of lineage and developmental stage-specific transcriptional programs. Here, we …

Chromatin remodeler complexes regulate gene transcription, DNA replication and DNA
repair by changing both nucleosome position and post-translational modifications. The …

Environmental endocrine disruptors (EEDs) seriously endanger human health by interfering
with the normal function of reproductive systems. In males, EEDs can affect sperm formation …

Background Prostate cancer is a clinically heterogeneous disease with a subset of patients
rapidly progressing to lethal‐metastatic prostate cancer. Current clinicopathological …