RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

Many RNA-binding proteins have modular structures and are composed of multiple repeats
of just a few basic domains that are arranged in various ways to satisfy their diverse …

The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …

With the amount of genetic information available, a lot of attention has focused on systems
biology, in particular biomolecular interactions. Considering the huge number of such …

In all organisms, RNA-binding proteins participate in modulating all the steps in the life cycle
of RNA, including transcription, folding, translation and turnover. In bacteria, RNA-binding …

RNA degradation is a major process controlling RNA levels and plays a central role in cell
metabolism. From the labile messenger RNA to the more stable noncoding RNAs (mostly …

The RNA degradosome is a massive multi-enzyme assembly that occupies a nexus in RNA
metabolism and post-transcriptional control of gene expression in Escherichia coli and many …

Human polynucleotide phosphorylase (hPNPase) is a 3′-to-5′ exoribonuclease that
degrades specific mRNA and miRNA, and imports RNA into mitochondria, and thus …

Post-transcriptional regulation enables bacteria to quickly response to environmental
stresses. Polynucleotide phosphorylase (PNPase), which contains an N-terminal catalytic …

RecJ is a single-stranded DNA (ssDNA)-specific 5′-3′ exonuclease that plays an
important role in DNA repair and recombination. To elucidate how RecJ achieves its high …