Proteolysis targeting chimeras (PROTACs) are heterobifunctional compounds that recruit the
E3 ubiquitin ligase machinery to proteins of interest, resulting in their ubiquitination and …

In order to accommodate the growing demand for positron emission tomography (PET), it
will be necessary to create innovative radiochemical and engineering technologies to …

Copper-mediated radiofluorination has demonstrated remarkable potential in forming
aromatic C–18F bonds of radioligands for positron emission tomography (PET). Achieving …

The increasing number of positron-emission tomography (PET) tracers being developed to
aid drug development and create new diagnostics has led to an increased need for …

Current equipment and methods for preparation of radiopharmaceuticals for positron
emission tomography (PET) are expensive and best suited for large-scale multi-doses …

Positron emission tomography (PET) is a powerful diagnostic tool that holds incredible
potential for clinicians to track a wide variety of biological processes using specialized …

New platforms are enabling radiochemistry to be carried out in tiny, microliter-scale volumes,
and this capability has enormous benefits for the production of radiopharmaceuticals. These …

Positron emission tomography (PET) has proven to be an invaluable tool in the staging and
management of disease in oncology; however,[18F] fluorodeoxyglucose ([18F] FDG) …

Recent droplet-based radiochemistry platforms have enabled reactions in< 10 µL volumes,
providing many advantages including minimal reagent consumption, fast synthesis times …

Background Current automated radiosynthesizers are generally optimized for producing
large batches of PET tracers. Preclinical imaging studies, however, often require only a …