BACKGROUND: The absolute risk of recurrences among patients using aspirin for prevention of cardiovascular events remains high. Persistent platelet reactivity despite …
L Jacobs, J Emmerechts, C Mathieu… - Environmental …, 2010 - ehp.niehs.nih.gov
Background Population studies suggest that persons with diabetes are more sensitive to the effects of particulate matter (PM) air pollution. However, the biological mechanisms of a …
M Crescente, A Di Castelnuovo… - Thrombosis and …, 2008 - thieme-connect.com
It was the aim of the present study to perform a systematic review of the published studies that estimated the prevalence of non-responders to aspirin, as assessed by the closure time …
G Kasotakis, II Pipinos, TG Lynch - Journal of vascular surgery, 2009 - Elsevier
Atherothrombosis, characterized by atherosclerotic plaque rupture and subsequent occlusive or subocclusive thrombus formation is the primary cause of acute ischemic …
PA Gurbel, US Tantry - Journal of interventional cardiology, 2006 - Wiley Online Library
The efficacy with aspirin and clopidogrel treatment has been demonstrated in various clinical trials. Laboratory evaluation of platelet response in recent studies revealed that a …
HW Cohen, JP Crandall, SM Hailpern… - Journal of diabetes and its …, 2008 - Elsevier
INTRODUCTION: Diabetes is known to be a prothrombotic state. Since serotonin uptake plays a role in both platelet activation and depression, we undertook to examine a …
M Pignone, CD Williams - Nature Reviews Endocrinology, 2010 - nature.com
Aspirin is effective for the prevention of cardiovascular events in patients with a history of vascular disease, as so-called secondary prevention. In general populations with no history …
SH Simpson, AS Abdelmoneim, D Omran… - The American Journal of …, 2014 - Elsevier
Background Randomized controlled trials have shown that≤ 100 mg aspirin daily is not effective for primary prevention of cardiovascular events in diabetes; however, clinical and …
AM Cerbone, N Macarone-Palmieri… - Acta …, 2009 - Springer
Diabetes mellitus is commonly associated with both microvascular and macrovascular complications (coronary artery disease, cerebrovascular events, severe peripheral vascular …