Antiplatelet drugs: a review of their pharmacology and management in the perioperative period

R Hall, CD Mazer - Anesthesia & Analgesia, 2011 - journals.lww.com
In the normal course of the delivery of care, anesthesiologists encounter many patients who
are receiving drugs that affect platelet function as a fundamental part of primary and …

Prevalence of persistent platelet reactivity despite use of aspirin: a systematic review

MMC Hovens, JD Snoep, JCJ Eikenboom… - American heart …, 2007 - Elsevier
BACKGROUND: The absolute risk of recurrences among patients using aspirin for
prevention of cardiovascular events remains high. Persistent platelet reactivity despite …

Air pollution–related prothrombotic changes in persons with diabetes

L Jacobs, J Emmerechts, C Mathieu… - Environmental …, 2010 - ehp.niehs.nih.gov
Background Population studies suggest that persons with diabetes are more sensitive to the
effects of particulate matter (PM) air pollution. However, the biological mechanisms of a …

Response variability to aspirin as assessed by the platelet function analyzer (PFA)-100

M Crescente, A Di Castelnuovo… - Thrombosis and …, 2008 - thieme-connect.com
It was the aim of the present study to perform a systematic review of the published studies
that estimated the prevalence of non-responders to aspirin, as assessed by the closure time …

[HTML][HTML] Current evidence and clinical implications of aspirin resistance

G Kasotakis, II Pipinos, TG Lynch - Journal of vascular surgery, 2009 - Elsevier
Atherothrombosis, characterized by atherosclerotic plaque rupture and subsequent
occlusive or subocclusive thrombus formation is the primary cause of acute ischemic …

Aspirin and clopidogrel resistance: consideration and management

PA Gurbel, US Tantry - Journal of interventional cardiology, 2006 - Wiley Online Library
The efficacy with aspirin and clopidogrel treatment has been demonstrated in various
clinical trials. Laboratory evaluation of platelet response in recent studies revealed that a …

Aspirin resistance associated with HbA1c and obesity in diabetic patients

HW Cohen, JP Crandall, SM Hailpern… - Journal of diabetes and its …, 2008 - Elsevier
INTRODUCTION: Diabetes is known to be a prothrombotic state. Since serotonin uptake
plays a role in both platelet activation and depression, we undertook to examine a …

Aspirin for primary prevention of cardiovascular disease in diabetes mellitus

M Pignone, CD Williams - Nature Reviews Endocrinology, 2010 - nature.com
Aspirin is effective for the prevention of cardiovascular events in patients with a history of
vascular disease, as so-called secondary prevention. In general populations with no history …

Prevalence of high on-treatment platelet reactivity in diabetic patients treated with aspirin

SH Simpson, AS Abdelmoneim, D Omran… - The American Journal of …, 2014 - Elsevier
Background Randomized controlled trials have shown that≤ 100 mg aspirin daily is not
effective for primary prevention of cardiovascular events in diabetes; however, clinical and …

Diabetes, vascular complications and antiplatelet therapy: open problems

AM Cerbone, N Macarone-Palmieri… - Acta …, 2009 - Springer
Diabetes mellitus is commonly associated with both microvascular and macrovascular
complications (coronary artery disease, cerebrovascular events, severe peripheral vascular …