Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease

DM Tebit, EJ Arts - The Lancet infectious diseases, 2011 - thelancet.com
Since the isolation of HIV, multiple transmissions are thought to have occurred between man
and other old-world primates. Assessment of samples from apes and human beings with …

How useful are the genetic markers in attempts to understand and manage marine biodiversity?

JP Féral - Journal of experimental marine biology and ecology, 2002 - Elsevier
The genetics of marine populations is a subject that has made little progress compared with
the effort spent on the terrestrial environment. This is so despite “applied” aspects such as …

Efficient targeted multiallelic mutagenesis in tetraploid potato (Solanum tuberosum) by transient CRISPR-Cas9 expression in protoplasts

M Andersson, H Turesson, A Nicolia, AS Fält… - Plant cell reports, 2017 - Springer
Key message Altered starch quality with full knockout of GBSS gene function in potato was
achieved using CRISPR-Cas9 technology, through transient transfection and regeneration …

CRISPR/Cas9-mediated mutagenesis of the RIN locus that regulates tomato fruit ripening

Y Ito, A Nishizawa-Yokoi, M Endo, M Mikami… - … and biophysical research …, 2015 - Elsevier
Site-directed mutagenesis using genetic approaches can provide a wealth of resources for
crop breeding as well as for biological research. The clustered regularly interspaced short …

Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination

KS Lole, RC Bollinger, RS Paranjape… - Journal of …, 1999 - Am Soc Microbiol
The development of an effective human immunodeficiency virus type 1 (HIV-1) vaccine is
likely to depend on knowledge of circulating variants of genes other than the commonly …

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

M Dean, M Carrington, C Winkler, GA Huttley… - Science, 1996 - science.org
The chemokine receptor 5 (CKR5) protein serves as a secondary receptor on CD4+ T
lymphocytes for certain strains of human immunodeficiency virus-type 1 (HIV-1). The CKR5 …

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

L Li, ID Krantz, YU Deng, A Genin, AB Banta… - Nature …, 1997 - nature.com
Alagille syndrome is an autosomal dominant disorder characterized by abnormal
development of liver, heart, skeleton, eye, face and, less frequently, kidney. Analyses of …

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

DR Burton, J Pyati, R Koduri, SJ Sharp, GB Thornton… - Science, 1994 - science.org
The ability of antibodies to neutralize diverse primary isolates of human immunodeficiency
virus-type 1 in vitro has been questioned, with implications for the likely efficacy of vaccines …

Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection

RAJ Shankarappa, JB Margolick, SJ Gange… - Journal of …, 1999 - Am Soc Microbiol
To understand the high variability of the asymptomatic interval between primary human
immunodeficiency virus type 1 (HIV-1) infection and the development of AIDS, we studied …

Identification of a new human immunodeficiency virus type 1 distinct from group M and group O

F Simon, P Mauclère, P Roques, I Loussert-Ajaka… - Nature medicine, 1998 - nature.com
A highly divergent HIV-1 isolate, designated YBF 30, was obtained in 1995 from a 40-year-
old Cameroonian woman with AIDS. Depending on the genes studied, phylogenetic …