Emergence of drug resistance has created unmet medical need for the development of new
classes of antibiotics. Discovery of new antibacterial agents with new mode of action …

The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

A class of quinazolone thiazoles was identified as new structural scaffolds for potential
antibacterial conquerors to tackle dreadful resistance. Some prepared compounds exhibited …

A novel series of benzimidazole-incorporated sulfonamide analogues were designed and
synthesized with an effort to overcome the increasing antibiotic resistance. Compound 5c …

Main observation and conclusion Novel quinazolonthiazoles were designed and
synthesized as new potential antimicrobial agents by facile multi‐step procedure from o …

Aminothiazolyl berberine derivatives as potentially antimicrobial agents were designed and
synthesized in an effort to overcome drug resistance. The antimicrobial assay revealed that …

A series of novel benzimidazole quinolones as potential antimicrobial agents were designed
and synthesized. Most of the prepared compounds exhibited good or even stronger …

A series of novel berberine-based imidazole derivatives as new type of antimicrobial agents
were developed and characterized. Most of them gave good antibacterial activity toward the …

Naphthalimide compounds are an important type of nitrogen-containing aromatic
heterocycles with cyclic double imides and the naphthalene framework. This π-deficient …

A series of 5-fluorouracil benzimidazoles as novel type of potential antimicrobial agents
were designed and synthesized for the first time. Bioactive assay manifested that some of …