Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases …

DI Tsilimigras, I Ntanasis-Stathopoulos, F Bagante… - Surgical oncology, 2018 - Elsevier
Background Hepatic resection is considered the optimal potentially curative treatment for
colorectal liver metastases (CRLM). Following resection, up to two-thirds of patients will …

Image-guided ablation for colorectal liver metastasis: principles, current evidence, and the path forward

YM Lin, I Paolucci, KK Brock, BC Odisio - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer is the fourth most common type of cancer globally.
Approximately 20% of patients with colorectal cancer present with synchronous liver …

Ablative margins of colorectal liver metastases using deformable CT image registration and autosegmentation

YM Lin, I Paolucci, CS O'Connor, BM Anderson… - Radiology, 2023 - pubs.rsna.org
Background Confirming ablation completeness with sufficient ablative margin is critical for
local tumor control following colorectal liver metastasis (CLM) ablation. An image-based …

Factors associated with local tumor control and complications after thermal ablation of colorectal cancer liver metastases: a 15-year retrospective cohort study

I Kurilova, A Bendet, EN Petre, FE Boas, E Kaye… - Clinical colorectal …, 2021 - Elsevier
Introduction The purpose of this study was to identify risk factors associated with local tumor
progression-free survival (LTPFS) and complications after colorectal liver metastases (CLM) …

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

R Vera, E González-Flores, C Rubio, J Urbano… - Clinical and …, 2020 - Springer
Colorectal cancer (CRC) has the second-highest tumor incidence and is a leading cause of
death by cancer. Nearly 20% of patients with CRC will have metastases at the time of …

Improved outcomes of thermal ablation for colorectal liver metastases: a 10-year analysis from the prospective Amsterdam CORE Registry (AmCORE)

RS Puijk, M Dijkstra, BAT van den Bemd… - Cardiovascular and …, 2022 - Springer
Background To analyze long-term oncological outcomes of open and percutaneous thermal
ablation in the treatment of patients with colorectal liver metastases (CRLM). Methods This …

3D margin assessment predicts local tumor progression after ablation of colorectal cancer liver metastases

N Vasiniotis Kamarinos, M Gonen… - International Journal …, 2022 - Taylor & Francis
Objective To determine the feasibility and prognostic value of 3D measuring of the ablation
margins using a dedicated image registration software. Methods This retrospective study …

Machine learning-based analysis of rectal cancer MRI radiomics for prediction of metachronous liver metastasis

M Liang, Z Cai, H Zhang, C Huang, Y Meng, L Zhao… - Academic radiology, 2019 - Elsevier
Rationale and Objectives To use machine learning-based magnetic resonance imaging
radiomics to predict metachronous liver metastases (MLM) in patients with rectal cancer …

Colorectal cancer liver metastases: Genomics and biomarkers with focus on local therapies

Y Kitsel, T Cooke, V Sotirchos, CT Sofocleous - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a leading cause of death among cancer
patients, and the liver is the most common visceral metastatic site. Despite promising …

The importance of optimal thermal ablation margins in colorectal liver metastases: a systematic review and meta-analysis of 21 studies

DD Chlorogiannis, VS Sotirchos, C Georgiades… - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer is a significant cause of cancer-related deaths in the US
and the fourth most common malignancy. Percutaneous thermal ablation (TA) is considered …