Evidence for the efficacy of systemic opioid-sparing analgesics in pediatric surgical populations: a systematic review

A Zhu, HA Benzon, TA Anderson - Anesthesia & Analgesia, 2017 - journals.lww.com
While a large number of studies has examined the efficacy of opioid-sparing analgesics in
adult surgical populations, fewer studies are available to guide postoperative pain treatment …

Opioid-free anesthesia: the pros and cons

V Carcamo-Cavazos… - Advances in …, 2022 - advancesinanesthesia.com
Along with the definition of pain, the treatment of pain has evolved as we continue to
understand the natural history of pain, the different kinds of pain, and the efficacy of various …

[PDF][PDF] Is opioid-free general anesthesia more superior for postoperative pain versus opioid general anesthesia in laparoscopic cholecystectomy?

M Toleska, A Dimitrovski - prilozi, 2019 - sciendo.com
Introduction: Opioid-free anesthesia (OFA) is a new anesthesiological technique, where the
giving of opioids (fentanyl) is avoided in the intra-and post-operative period. This leads to …

[HTML][HTML] Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced …

R Root-Bernstein - Pharmaceuticals, 2022 - mdpi.com
This paper proposes the design of combination opioid–adrenergic tethered compounds to
enhance efficacy and specificity, lower dosage, increase duration of activity, decrease side …

Intra-operative esmolol and pain following mastectomy: A randomised clinical trial

FT Mendonça, AJ Tramontini, HI Miake… - European Journal of …, 2021 - journals.lww.com
Intra-operative esmolol and pain following mastectomy: A ran... : European Journal of
Anaesthesiology | EJA Intra-operative esmolol and pain following mastectomy: A randomised …

Does the β-receptor antagonist esmolol have analgesic effects?: A randomised placebo-controlled cross-over study on healthy volunteers undergoing the cold pressor …

F Ander, A Magnuson, A de Leon… - European Journal of …, 2018 - journals.lww.com
BACKGROUND Esmolol may attenuate the sympathetic response to pain and reduce
postoperative opioid consumption. It is not clear whether esmolol has an analgesic effect per …

[HTML][HTML] Labetalol as an alternative to esmolol and fentanyl for maintaining hemodynamic stability during laparoscopic surgery: Comparative effects on recovery …

OLE Lazo, PF White, R Yumul, F Yumul… - Journal of Surgery …, 2020 - fortuneonline.org
β-blockers like labetalol and esmolol have been successfully used for controlling acute
autonomic responses during surgery. Objective: To compare the intraoperative use of …

盐酸艾司洛尔联合右美托咪定对肺癌患者应激反应和Th1/Th2 型细胞因子的影响.

张秋实, 刘欢, 周易, 马垚, 李笑东… - Progress in Modern …, 2023 - search.ebscohost.com
摘要目的: 探讨盐酸艾司洛尔联合右美托咪定对肺癌患者应激反应和辅助性T 细胞1 (Th1)/Th2
型细胞因子的影响. 方法: 选取武汉科技大学附属天佑医院2020 年6 月~ 2022 年3 …

A comparative analysis of the effects of esmolol, lidocaine, nitroglycerin and placebo on hemodynamic response to extubation, and extubation quality and …

G Kucukosman, BG Aydin - 2020 - annalsmedres.org
Aim: To comparatively analyze and determine the effects of esmolol, lidocaine, and
nitroglycerin on hemodynamic response to extubation, extubation quality and postoperative …

Esmolol infusion versus propranolol infusion: effects on heart rate and blood pressure in healthy volunteers

MD Muller, TA Ahmad… - Journal of Applied …, 2017 - journals.physiology.org
Despite its widespread clinical use, the β1-adrenergic receptor antagonist esmolol
hydrochloride is not commonly used in human physiology research, and the effective dose …