Oncolytic virus (OV) therapy is an emerging anti-cancer approach that utilizes viruses to
preferentially infect and kill cancer cells, while not harming healthy cells. Vesicular stomatitis …

Oncolytic virus (OV) therapy is an anti-cancer approach that uses viruses that preferentially
infect, replicate in and kill cancer cells. Vesicular stomatitis virus (VSV, a rhabdovirus) is an …

Oncolytic viruses represent an exciting new aspect of the evolving field of cancer
immunotherapy. We have engineered a novel hybrid vector comprising vesicular stomatitis …

Vesicular stomatitis virus (VSV) has long been regarded as a promising recombinant
vaccine platform and oncolytic agent but has not yet been tested in humans because it …

Oncolytic viruses have gained much attention in recent years, due, not only to their ability to
selectively replicate in and lyse tumor cells, but to their potential to stimulate antitumor …

Newcastle disease virus (NDV) is an intrinsically tumor-specific virus, which is currently
under investigation as a clinical oncolytic agent. Several clinical trials have reported NDV to …

Oncolytic viruses are under intense development and have earned their place among the
novel class of cancer immunotherapeutics that are changing the face of cancer therapy …

With advances in cancer biology and an ever‐deepening understanding of molecular
virology, oncolytic virus (OV)‐driven therapies have developed rapidly and become a …

Toxicology studies were performed in rats and rhesus macaques to establish a safe starting
dose for intratumoral injection of an oncolytic vesicular stomatitis virus expressing human …

Oncolytic viruses are promising new agents in cancer therapy. Success of tumor lysis is
often hampered by low intra-tumoral titers due to a strong anti-viral host immune response …