[HTML][HTML] Ischemia/reperfusion

T Kalogeris, CP Baines, M Krenz… - Comprehensive …, 2016 - ncbi.nlm.nih.gov
Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Cell biology of ischemia/reperfusion injury

T Kalogeris, CP Baines, M Krenz, RJ Korthuis - International review of cell …, 2012 - Elsevier
Disorders characterized by ischemia/reperfusion (I/R), such as myocardial infarction, stroke,
and peripheral vascular disease, continue to be among the most frequent causes of …

PBMDA: A novel and effective path-based computational model for miRNA-disease association prediction

ZH You, ZA Huang, Z Zhu, GY Yan, ZW Li… - PLoS computational …, 2017 - journals.plos.org
In the recent few years, an increasing number of studies have shown that microRNAs
(miRNAs) play critical roles in many fundamental and important biological processes. As …

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

E Van Rooij, EN Olson - Nature reviews Drug discovery, 2012 - nature.com
In recent years, prominent roles for microRNAs (miRNAs) have been uncovered in several
cardiovascular disorders. The ability to therapeutically manipulate miRNA expression and …

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development

L Maegdefessel, JM Spin, U Raaz, SM Eken… - Nature …, 2014 - nature.com
Identification and treatment of abdominal aortic aneurysm (AAA) remain among the most
prominent challenges in vascular medicine. MicroRNAs (miRNAs) are crucial regulators of …

Emerging roles for microRNAs in diabetic microvascular disease: novel targets for therapy

Y Zhang, X Sun, B Icli, MW Feinberg - Endocrinology Reviews, 2017 - academic.oup.com
Chronic, low-grade systemic inflammation and impaired microvascular function are critical
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …

[HTML][HTML] Noncoding RNAs in acute kidney injury

T Brandenburger, AS Somoza, Y Devaux… - Kidney International, 2018 - Elsevier
Acute kidney injury (AKI) is an important health issue concerning∼ 50% of patients treated
in intensive care units. AKI mainly occurs after sepsis, acute ischemia, nephrotoxicity, or …

MicroRNA-26a regulates pathological and physiological angiogenesis by targeting BMP/SMAD1 signaling

B Icli, AKM Wara, J Moslehi, X Sun, E Plovie… - Circulation …, 2013 - Am Heart Assoc
Rationale: The rapid induction and orchestration of new blood vessels are critical for tissue
repair in response to injury, such as myocardial infarction, and for physiological angiogenic …

LMTRDA: Using logistic model tree to predict MiRNA-disease associations by fusing multi-source information of sequences and similarities

L Wang, ZH You, X Chen, YM Li, YN Dong… - PLoS computational …, 2019 - journals.plos.org
Emerging evidence has shown microRNAs (miRNAs) play an important role in human
disease research. Identifying potential association among them is significant for the …

The multifactorial nature of microRNAs in vascular remodelling

SMJ Welten, EAC Goossens, PHA Quax… - Cardiovascular …, 2016 - academic.oup.com
Vascular remodelling is a multifactorial process that involves both adaptive and maladaptive
changes of the vessel wall through, among others, cell proliferation and migration, but also …