Transposable phage Mu has played a historic role in the development of the mobile DNA
element field (1). The very first paper that christened this phage after its mu tator properties …

The topological properties of DNA molecules, supercoiling, knotting, and catenation, are
intimately connected with essential biological processes, such as gene expression …

This article traces the pioneering contributions of phage Mu to our current knowledge of how
movable elements move/transpose. Mu provided the first molecular evidence of insertion …

The advantages of phage Mu transposition-based systems for the chromosomal editing of
plasmid-less strains are reviewed. The cis and trans requirements for Mu phage-mediated …

DNA transposases are enzymes that catalyze the movement of discrete pieces of DNA from
one location in the genome to another. Transposition occurs through a series of controlled …

Phage Mu transposes by two distinct pathways depending on the specific stage of its life
cycle. A common θ strand transfer intermediate is resolved differentially in the two pathways …

We describe a new immunity mechanism that protects actively replicating/transposing Mu
from self-integration. We show that this mechanism is distinct from the established cis …

We develop topological methods for analyzing difference topology experiments involving 3–
string tangles. Difference topology is a novel technique used to unveil the structure of stable …

Difference topology is an experimental technique that can be used to unveil the topological
structure adopted by two or more DNA segments in a stable protein–DNA complex …

DNA transactions in biological systems are often carried out by multisubunit protein
assemblies that confer a defined topology on their DNA target sites. A subset of …