Cortactin: A major cellular target of viral, protozoal, and fungal pathogens
I Sharafutdinov, B Friedrich, K Rottner… - Molecular …, 2024 - Wiley Online Library
Many viral, protozoal, and fungal pathogens represent major human and animal health
problems due to their great potential of causing infectious diseases. Research on these …
problems due to their great potential of causing infectious diseases. Research on these …
Disulfidptosis: a novel cell death modality induced by actin cytoskeleton collapse and a promising target for cancer therapeutics
T Li, Y Song, L Wei, X Song, R Duan - Cell Communication and Signaling, 2024 - Springer
Disulfidptosis is a novel discovered form of programmed cell death (PCD) that diverges from
apoptosis, necroptosis, ferroptosis, and cuproptosis, stemming from disulfide stress-induced …
apoptosis, necroptosis, ferroptosis, and cuproptosis, stemming from disulfide stress-induced …
[HTML][HTML] Cortactin-dependent control of Par1b-regulated epithelial cell polarity in Helicobacter infection
I Sharafutdinov, A Harrer, M Müsken, K Rottner… - Cell Insight, 2024 - Elsevier
Cell polarity is crucial for gastric mucosal barrier integrity and mainly regulated by polarity-
regulating kinase partitioning-defective 1b (Par1b). During infection, the carcinogen …
regulating kinase partitioning-defective 1b (Par1b). During infection, the carcinogen …
CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes
The inhibitors, CK-666 and CK-869, are widely used to probe the function of Arp2/3 complex
mediated actin nucleation in vitro and in cells. However, in mammals, the Arp2/3 complex …
mediated actin nucleation in vitro and in cells. However, in mammals, the Arp2/3 complex …
Reconstitution of Arp2/3-nucleated actin assembly with proteins CP, V-1, and CARMIL
OL Mooren, P McConnell, JD DeBrecht, A Jaysingh… - Current Biology, 2024 - cell.com
Actin polymerization is often associated with membrane proteins containing capping-protein-
interacting (CPI) motifs, such as capping protein, Arp2/3, myosin I linker (CARMIL), CD2AP …
interacting (CPI) motifs, such as capping protein, Arp2/3, myosin I linker (CARMIL), CD2AP …
[HTML][HTML] Reconstitution of Arp2/3-Nucleated Actin Assembly with CP, V-1 and CARMIL
OL Mooren, P McConnell, JD DeBrecht, A Jaysingh… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Actin polymerization is often associated with membrane proteins containing capping-protein-
interacting (CPI) motifs, such as CARMIL, CD2AP, and WASHCAP/Fam21. CPI motifs bind …
interacting (CPI) motifs, such as CARMIL, CD2AP, and WASHCAP/Fam21. CPI motifs bind …
Visualizing the nucleating and capped states of f-actin by Ca2+-gelsolin: Saxs data based structures of binary and ternary complexes
A Sagar, N Peddada, V Choudhary, Y Mir… - International Journal of …, 2024 - Elsevier
Structural insight eludes on how full-length gelsolin depolymerizes and caps filamentous (F-
) actin, while the same entity can nucleate polymerization of G-actins. Analyzing small angle …
) actin, while the same entity can nucleate polymerization of G-actins. Analyzing small angle …