Cognitive impairment in people living with HIV: mechanisms, controversies, and future perspectives

CD Moschopoulos, K Alford, A Antoniadou… - Trends in Molecular …, 2024 - cell.com
Despite the dramatic decrease in HIV-associated neurocognitive impairment (NCI) in the
combined antiretroviral treatment (cART) era, subtler neuropsychological complications …

Global systematic review of common mental health disorders in adults living with HIV

J Hoare, T Sevenoaks, B Mtukushe, T Williams… - Current HIV/AIDS …, 2021 - Springer
Purpose of the review By reviewing the most recent common mental health disorders
(CMHD) studies in people living with HIV (PLWH)(2018-2020), this review discusses the …

Twelve-year neurocognitive decline in HIV is associated with comorbidities, not age: a CHARTER study

RK Heaton, RJ Ellis, B Tang, CM Marra, LH Rubin… - Brain, 2023 - academic.oup.com
Modern antiretroviral therapy (ART) has increased longevity of people with HIV and shifted
the age distribution of the HIV pandemic upward toward that of the general population. This …

Lower CSF homovanillic acid relates to higher burden of neuroinflammation and depression in people with HIV disease

R Saloner, M Cherner, DJ Grelotti, EW Paolillo… - Brain, behavior, and …, 2020 - Elsevier
Background HIV-related neuroinflammation has been proposed as a catalyst for
dopaminergic dysregulation in mesocortical pathways, which may contribute to the …

The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition

JM Rogers, JE Iudicello, MCG Marcondes, EE Morgan… - Viruses, 2023 - mdpi.com
Objective: Methamphetamine and cannabis are two widely used substances among people
living with HIV (PLWH). Whereas methamphetamine use has been found to worsen HIV …

Chronically elevated depressive symptoms interact with acute increases in inflammation to predict worse neurocognition among people with HIV

R Saloner, EW Paolillo, RK Heaton, DJ Grelotti… - Journal of …, 2021 - Springer
We examined the joint effects of depressive symptoms (Beck Depression Inventory-II (BDI-
II)) and systemic inflammation (plasma C-reactive protein (CRP)) on longitudinal profiles of …

Heterogeneity in longitudinal trajectories of cognitive performance among middle-aged and older individuals with hypertension: Growth mixture modeling across an 8 …

B Zhang, S Jiang - Hypertension Research, 2022 - nature.com
Hypertension is one of the most prevalent chronic conditions and has been proven to be
related to cognitive function. However, there is no evidence regarding the heterogeneity in …

The new profile of psychiatric disorders in patients with HIV infection.

L Gallego Deike, P Barreiro, B Reneses - AIDS reviews, 2023 - search.ebscohost.com
Nowadays, HIV infection is largely considered as a chronic condition rather than a deadly
disease, given that effective antiretroviral treatment allows almost complete and persistent …

Depression is associated with hippocampal volume loss in adults with HIV

M Bronshteyn, FN Yang, KF Shattuck… - Human brain …, 2021 - Wiley Online Library
Depressive symptoms are more prevalent in persons with HIV (PWH) than HIV‐uninfected
individuals. In HIV‐uninfected individuals, depression has been associated with atrophy in …

Neuropsychiatric disorders, emotional disturbances, and their associations with HIV-associated neurocognitive disorder

JA Muñoz-Moreno, LA Cysique, SB Rourke - … Complications of HIV …, 2021 - Springer
The current chapter provides a critical and narrative review of recent research on the
neuropsychiatric disorders, emotional disturbances, and their associations with …