The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …

Angiogenesis, or the formation of new blood vessels from the preexisting vasculature, is a
key component in numerous physiologic and pathologic responses and has broad impact in …

Adhesion G protein-coupled receptors (aGPCRs) constitute an evolutionarily ancient family
of receptors that often undergo autoproteolysis to produce α and β subunits,–. A tethered …

Adhesion G protein–coupled receptors (AGPCRs) are a thirty-three-member subfamily of
Class B GPCRs that control a wide array of physiological processes and are implicated in …

Adhesion-type heterotrimeric guanine nucleotide–binding protein (G protein)–coupled
receptors (Adhesion-GPCRs) comprise a class of widely distributed seven-transmembrane …

Despite the critical role of endothelial Wnt/β-catenin signaling during central nervous system
(CNS) vascularization, how endothelial cells sense and respond to specific Wnt ligands and …

The orphan G protein–coupled receptor (GPCR) GPR124/tumor endothelial marker 5 is
highly expressed in central nervous system (CNS) endothelium. Here, we show that …

β-Catenin signaling controls the development and maintenance of the blood–brain barrier
(BBB) and the blood–retina barrier (BRB), but the division of labor and degree of …

Adhesion G protein-coupled receptors: structure, signaling, physiology, and
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …

The G protein-coupled receptor (GPCR) family comprises the largest class of cell surface
receptors found in metazoan proteomes. Within the novel GPCR subfamily of adhesion …