Eosinophils and helminth infection: protective or pathogenic?

E Mitre, AD Klion - Seminars in immunopathology, 2021 - Springer
Since the earliest descriptions of this enigmatic cell, eosinophils have been implicated in
both protective and pathogenic immune responses to helminth infection. Nevertheless …

Effects of helminths and anthelmintic treatment on cardiometabolic diseases and risk factors: A systematic review

K Pham, A Mertelsmann, K Mages… - PLOS Neglected …, 2023 - journals.plos.org
Background Globally, helminth infections and cardiometabolic diseases often overlap in
populations and individuals. Neither the causal relationship between helminth infections …

The helminth glycoprotein omega‐1 improves metabolic homeostasis in obese mice through type 2 immunity‐independent inhibition of food intake

HJP van Der Zande, MA Gonzalez… - The FASEB …, 2021 - Wiley Online Library
Type 2 immunity plays an essential role in the maintenance of metabolic homeostasis and
its disruption during obesity promotes meta‐inflammation and insulin resistance. Infection …

Association of Strongyloides stercoralis infection and type 2 diabetes mellitus in northeastern Thailand: Impact on diabetic complication-related renal biochemical …

M Yingklang, A Chaidee, R Dangtakot, C Jantawong… - PLoS …, 2022 - journals.plos.org
Background Several studies have demonstrated that helminth infections provide a degree of
protection against Type 2 diabetes mellitus (T2DM). However, the relationship between …

Effects of a novel polyphenol-rich plant extract on body composition, inflammation, insulin sensitivity, and glucose homeostasis in obese mice

HJP van der Zande, JM Lambooij… - International Journal of …, 2021 - nature.com
Background/objectives The worldwide prevalence of obesity, metabolic syndrome and type
2 diabetes (T2D) is reaching epidemic proportions that urge the development of new …

Helminth Infections and Diabetes: Mechanisms Accounting for Risk Amelioration

A Rajamanickam, S Babu - Annual Review of Nutrition, 2024 - annualreviews.org
The global prevalence of type 2 diabetes is increasing rapidly, with an anticipated 600
million cases by 2035. While infectious diseases such as helminth infections have …

Helminth infection and helminth-derived products: A novel therapeutic option for non-alcoholic fatty liver disease

X Liu, Y Jiang, J Ye, X Wang - Frontiers in immunology, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is closely related to obesity, diabetes, and
metabolic syndrome (MetS), and it has become the most common chronic liver disease …

Harnessing Schistosoma-associated metabolite changes in the human host to identify biomarkers of infection and morbidity: Where are we and what should we do …

M Kameni, F Musaigwa, LM Kamguia… - PLOS Neglected …, 2024 - journals.plos.org
Schistosomiasis is the second most widespread parasitic disease affecting humans. A key
component of today's infection control measures is the diagnosis and monitoring of infection …

Identification of trans-genus biomarkers for early diagnosis of intestinal schistosomiasis and progression of gut pathology in a mouse model using metabolomics

P Chienwichai, P Tipthara, J Tarning… - PLOS Neglected …, 2024 - journals.plos.org
Schistosomiasis is one of the most devastating human diseases worldwide. The disease is
caused by six species of Schistosoma blood fluke; five of which cause intestinal …

[HTML][HTML] Schistosomiasis in Gabon from 2000 to 2021-A review

JC Dejon-Agobé, JR Edoa, AA Adegnika… - Acta tropica, 2022 - Elsevier
Introduction Schistosomiasis is a public health issue of concern in Gabon, with the disease
being reported from all regions of the country. The topic has been of interest for the local …