Cell adhesion to the extracellular matrix has important roles in tissue integrity and human
health. Integrins are heterodimeric cell surface receptors that are composed by two non …

Galectins, a family of evolutionarily conserved glycan-binding proteins, play key roles in
diverse biological processes including tissue repair, adipogenesis, immune cell …

In humans, the placenta provides the only fetomaternal connection and is essential for
establishing a pregnancy as well as fetal well-being. Additionally, it allows maternal …

The first reported receptor for SARS-CoV-2 on host cells was the angiotensin-converting
enzyme 2 (ACE2). However, the viral spike protein also has an RGD motif, suggesting that …

Fetal growth restriction (FGR), which most commonly results from suboptimal placental
function, substantially increases risks for adverse perinatal and long-term outcomes. The …

Pregnancy-specific glycoproteins (PSGs) are members of the immunoglobulin superfamily
and are closely related to the predominantly membrane-bound CEACAM proteins. PSGs are …

Placentation is a major determinant of the success of pregnancy. It is regulated by several
factors such as cell adhesion molecules, tight junctions, and gap junctions. The cell …

Colorectal carcinoma (CRC) is a leading cause of cancer mortality. Tumorigenesis is a
dynamic process wherein cancer stem cells (CSCs) and their microenvironment promote …

Hypertensive disorders of pregnancy (HDP) are one of the commonest maladies, affecting
5%–10% of pregnancies worldwide. The American College of Obstetricians and …

Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many
processes required for a successful pregnancy. Over the past decades, increasing evidence …