Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Q Tuo, S Zhang, P Lei - Medicinal research reviews, 2022 - Wiley Online Library
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Isatin and its derivatives: a survey of recent syntheses, reactions, and applications

R Kakkar - MedChemComm, 2019 - pubs.rsc.org
Isatin (1H-indole-2, 3-dione) and its derivatives represent an important class of heterocyclic
compounds that can be used as precursors for drug synthesis. Since its discovery, a lot of …

Indole compounds may be promising medicines for ulcerative colitis

S Sugimoto, M Naganuma, T Kanai - Journal of gastroenterology, 2016 - Springer
Indole compounds are extracted from indigo plants and have been used as blue or purple
dyes for hundreds of years. In traditional Chinese medicine, herbal agents in combination …

In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α …

H Bu, S Tang, G Liu, C Miao, X Zhou, H Yang, B Liu - Toxicology, 2023 - Elsevier
Dibutyl phthalate (DBP) is widely used in perfumes, cosmetics, shampoos and medical
devices. It is ubiquitous in the environment and greatly endangers people's health. Several …

[HTML][HTML] Recent advances in the application of isoindigo derivatives in materials chemistry

AV Bogdanov, VF Mironov - Beilstein Journal of Organic …, 2021 - beilstein-journals.org
In this review, the data on the application of isoindigo derivatives in the chemistry of
functional materials are analyzed and summarized. These bisheterocycles can be used in …

Pure-water-soluble colorimetric chemosensors for highly sensitive and rapid detection of hydrogen sulfide: Applications to evaluation of on-site water quality and real …

HW Chun, J Zheng, EH Lee, BM Oh, CB Lee… - Sensors and Actuators B …, 2024 - Elsevier
Hydrogen sulfide (H 2 S) has adverse effects on humans in various routes through water
and air. However, the versatile detection of hydrogen sulfide (H 2 S) gas in various …

[图书][B] Cancer inhibitors from Chinese natural medicines

JP Xu - 2016 - taylorfrancis.com
Nature is an attractive source of therapeutic and preventive compounds, and with such
chemical diversity found in millions of species of plants, over 60% of currently used …

Discovery of a Meisoindigo-Derived PROTAC as the ATM Degrader: Revolutionizing Colorectal Cancer Therapy via Synthetic Lethality with ATR Inhibitors

TT Liu, Q Wang, Y Zhou, B Ye, T Liu… - Journal of Medicinal …, 2024 - ACS Publications
Meisoindigo (Mei) has long been recognized in chronic myeloid leukemia (CML) treatment.
To elucidate its molecular target and mechanisms, we embarked on designing and …

The Sources, Structures and Cytotoxicity of Animal‐Derived Bisindole Compounds

ZL Zhang, HN Xu, CM Gong, YZ Li, YM Li… - Chemistry & …, 2024 - Wiley Online Library
Bisindole compounds constitute a significant class of natural compounds distinguished by
their characteristic bisindole structure and renowned for their anticancer properties. Over the …

Stable Internal Reference Genes for Normalizing Real-Time Quantitative PCR in Baphicacanthus cusia under Hormonal Stimuli and UV Irradiation, and in Different …

Y Huang, H Tan, J Yu, Y Chen, Z Guo… - Frontiers in plant …, 2017 - frontiersin.org
Baphicacanthus cusia (Nees) Bremek, the plant source for many kinds of drugs in traditional
Chinese medicine, is widely distributed in South China, especially in Fujian. Recent studies …