The application of Fourier transform infrared microspectroscopy for the study of diseased central nervous system tissue

S Caine, P Heraud, MJ Tobin, D McNaughton… - Neuroimage, 2012 - Elsevier
In the last two decades the field of infrared spectroscopy has seen enormous advances in
both instrumentation and the development of bioinformatic methods for spectral analysis …

FTIR spectro-imaging of collagens for characterization and grading of gliomas

R Noreen, M Moenner, Y Hwu, C Petibois - Biotechnology advances, 2012 - Elsevier
Collagens are a family of at least 30 protein types organized as networks. They constitute
the main support material of cells under the form of extracellular matrix as well as for …

Diagnostic segregation of human brain tumours using Fourier-transform infrared and/or Raman spectroscopy coupled with discriminant analysis

K Gajjar, LD Heppenstall, W Pang, KM Ashton… - Analytical …, 2013 - pubs.rsc.org
The most common initial treatment received by patients with a brain tumour is surgical
removal of the growth. Precise histopathological diagnosis of brain tumours is to some …

Label-free delineation of brain tumors by coherent anti-Stokes Raman scattering microscopy in an orthotopic mouse model and human glioblastoma

O Uckermann, R Galli, S Tamosaityte, E Leipnitz… - PloS one, 2014 - journals.plos.org
Background Coherent anti-Stokes Raman scattering (CARS) microscopy provides fine
resolution imaging and displays morphochemical properties of unstained tissue. Here, we …

Tumor margin identification and prediction of the primary tumor from brain metastases using FTIR imaging and support vector machines

N Bergner, BFM Romeike, R Reichart, R Kalff, C Krafft… - Analyst, 2013 - pubs.rsc.org
Infrared spectroscopy enables the identification of tissue types based on their inherent
vibrational fingerprint without staining in a nondestructive way. Here, Fourier transform …

FTIR imaging of tissues: techniques and methods of analysis

K Malek, BR Wood, KR Bambery - Optical spectroscopy and …, 2014 - Springer
In this chapter, we describe biomedical applications of infrared microscopic imaging applied
to human tissue sections. The central focus is human diseases including cervical cancer …

Probing biochemical differences in lipid components of human cells by means of ATR-FTIR spectroscopy

M Portaccio, B Faramarzi, M Lepore - Biophysica, 2023 - mdpi.com
Infrared spectroscopy has emerged as a promising technique for studying the composition of
biological samples like lipids that play important roles in cellular functions and are involved …

Label-free biomedical imaging with mid-IR spectroscopy

MJ Walsh, RK Reddy… - IEEE Journal of selected …, 2012 - ieeexplore.ieee.org
IR absorption imaging, especially using Fourier transform IR (FT-IR) imaging spectrometers,
is an emerging modality for biomedical applications. As opposed to current techniques that …

Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury

SG Ustaoglu, MHM Ali, F Rakib, ELA Blezer… - Scientific reports, 2021 - nature.com
Traumatic brain injury (TBI) is the main cause of disability and mortality in individuals under
the age of 45 years. Elucidation of the molecular and structural alterations in brain tissue …

Vibrational micro-spectroscopy of human tissues analysis

AA Bunaciu, VD Hoang… - Critical Reviews in …, 2017 - Taylor & Francis
Vibrational spectroscopy (Infrared (IR) and Raman) and, in particular, micro-spectroscopy
and micro-spectroscopic imaging have been used to characterize developmental changes …