Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

During osteoarthritis (OA), angiogenesis is increased in the synovium, osteophytes and
menisci and leads to ossification in osteophytes and the deep layers of articular cartilage …

Recent studies indicate that, in addition to its neuropoietic actions, brain derived
neurotrophic factor (BDNF) promotes endothelial cell survival and induces neoangiogenesis …

Diabetic foot ulcer has become a worldwide clinical medical challenge as traditional
treatments are not effective enough to reduce the amputation rate. Therefore, it is of great …

BACKGROUND Pain remains the cardinal symptom of endometriosis. However, to date, the
underlying mechanisms are still only poorly understood. Increasing evidence points towards …

Growth of collateral blood vessels (arteriogenesis) is potentially able to preserve structure
and function of limbs and organs after occlusion of a major artery. The success of the …

Therapeutic induction of vascular growth may provide a treatment option for those patients
with myocardial or peripheral ischemia who are not suited to conventional revascularization …

The neurotrophin brain-derived neurotrophic factor (BDNF) is required for the maintenance
of cardiac vessel wall stability during embryonic development through direct angiogenic …

The term angiogenesis derives from the Greek words' angeio'meaning blood vessel,
and'genesis' meaning production or birth, together referring to the creation of blood vessels …

Therapeutic angiogenesis/vasculogenesis represents a new approach to treating patients
with ischemic disease not curable with conventional treatment. Manipulation of the …