Neuropathology and structural changes in hydrocephalus

MR Del Bigio - Developmental disabilities research reviews, 2010 - Wiley Online Library
In the context of spina bifida, hydrocephalus is usually caused by crowding of the posterior
fossa with obstruction to cerebrospinal fluid flow from the forth ventricle, and less often by …

Pathophysiology of congenital and neonatal hydrocephalus

JP McAllister II - Seminars in Fetal and Neonatal Medicine, 2012 - Elsevier
The pathophysiology of congenital and neonatal hydrocephalus is not well understood
although the prognosis for patients with this disorder is far from optimal. A major obstacle to …

Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter

M Garcia-Bonilla, L Castaneyra-Ruiz, S Zwick… - Fluids and barriers of the …, 2022 - Springer
Background Hydrocephalus is a neurological disease with an incidence of 80–125 per
100,000 births in the United States. Neuropathology comprises ventriculomegaly …

Priorities for hydrocephalus research: report from a National Institutes of Health–sponsored workshop

MA Williams, JP McAllister, ML Walker… - Journal of …, 2007 - thejns.org
Object Treatment for hydrocephalus has not advanced appreciably since the advent of
cerebrospinal fluid (CSF) shunts more than 50 years ago. Many questions remain that …

The neuropsychology of patients with clinically diagnosed idiopathic normal pressure hydrocephalus

P Hellström, M Edsbagge, T Archer, M Tisell… - …, 2007 - journals.lww.com
OBJECTIVE: To compare the neuropsychological performance of patients with idiopathic
normal pressure hydrocephalus (INPH) with that of healthy individuals and to examine its …

Reduction of astrogliosis and microgliosis by cerebrospinal fluid shunting in experimental hydrocephalus

JM Miller, JP McAllister II - Cerebrospinal Fluid Research, 2007 - Springer
Background Reactive gliosis has the potential to alter biomechanical properties of the brain,
impede neuronal regeneration and affect plasticity. Determining the onset and progression …

Neurodevelopmental outcomes after ventriculoperitoneal shunt placement in children with non-infectious hydrocephalus: a meta-analysis

M Sobana, D Halim, JK Aviani, U Gamayani… - Child's Nervous …, 2021 - Springer
Background Hydrocephalus is diagnosed when an accumulating amount of cerebrospinal
fluid (CSF) fails to circulate and/or absorbed in the ventricular system. Based on its etiology …

Neonatal brain hemorrhage (NBH) of prematurity: translational mechanisms of the vascular-neural network

T Lekic, D Klebe, R Poblete, PR Krafft… - Current medicinal …, 2015 - ingentaconnect.com
Neonatal brain hemorrhage (NBH) of prematurity is an unfortunate consequence of preterm
birth. Complications result in shunt dependence and long-term structural changes such as …

Opportunities in posthemorrhagic hydrocephalus research: outcomes of the Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop

JE Koschnitzky, RF Keep, DD Limbrick… - Fluids and Barriers of …, 2018 - Springer
Abstract The Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop was
held on July 25 and 26, 2016 at the National Institutes of Health. The workshop brought …

Reduced subventricular zone proliferation and white matter damage in juvenile ferrets with kaolin-induced hydrocephalus

DL Di Curzio, RJ Buist, MR Del Bigio - Experimental neurology, 2013 - Elsevier
Hydrocephalus is a neurological condition characterized by altered cerebrospinal fluid
(CSF) flow with enlargement of ventricular cavities in the brain. A reliable model of …