Diabetes mellitus is one of the major public health problems worldwide. Considerable recent
evidence suggests that the cellular reduction-oxidation (redox) imbalance leads to oxidative …

The consumption of plant-based food is important for health promotion, especially
concerning the prevention and management of chronic diseases. Flavonoids are the main …

Vascular complications are the major causes of death in patients with diabetes, and
endothelial dysfunction is the earliest event in vascular complications of diabetes. It has …

Type 2 diabetes mellitus is a leading cause of morbidity and mortality worldwide, given its
serious associated complications. Despite constant efforts and intensive research, an …

Zinc is an essential micronutrient for human health and is involved in various biological
functions, such as growth, metabolism, and immune function. In recent years, research on …

Receptor for advanced glycation end products (RAGE) is an immunoglobulin-like receptor
present on cell surface. RAGE binds to an array of structurally diverse ligands, acts as a …

Abstract Background/aims Rehmanniae Radix (RR) and Cornus officinalis (CO) are a typical
herbal pair used to treat diabetic nephropathy (DN) in clinical practice. DN can be effectively …

The pathophysiological mechanisms underlying the close relationship between
nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are multiple …

Diabetes mellitus is a major debilitating disease whose global incidence is progressively
increasing with currently over 463 million adult sufferers and this figure will likely reach over …

Epigenetics is involved in the altered expression of gene networks that underlie insulin
resistance and insufficiency. Major genes controlling β-cell differentiation and function, such …