Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …

White adipose tissue, once regarded as morphologically and functionally bland, is now
recognized to be dynamic, plastic and heterogenous, and is involved in a wide array of …

Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular
composition under physiological and pathophysiological conditions. The emergence of …

Connections between the gut and brain monitor the intestinal tissue and its microbial and
dietary content, regulating both physiological intestinal functions such as nutrient absorption …

Tissue clearing of gross anatomical samples was first described more than a century ago
and has only recently found widespread use in the field of microscopy. This renaissance has …

Mutations in the leptin gene (ob) result in a metabolic disorder that includes severe obesity,
and defects in thermogenesis and lipolysis, both of which are adipose tissue functions …

Tumour innervation is associated with worse patient outcomes in multiple cancers,, which
suggests that it may regulate metastasis. Here we observed that highly metastatic mouse …

Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Neuronal cell types are the nodes of neural circuits that determine the flow of information
within the brain. Neuronal morphology, especially the shape of the axonal arbor, provides …