Leishmaniasis is a neglected tropical disease that affects about 350 million individuals
worldwide. The protozoan parasite has a relatively simple life cycle with two principal …

Since the great discovery of Furchgott, Ignarro and Murad in the late 90's, nitric oxide (NO) is
considered one of the most versatile endogenous molecules, which is involved in important …

Leishmaniasis is caused by protozoan parasites of the genus Leishmania and causes a
wide spectrum of clinical manifestations ranging from self-healing cutaneous lesions to the …

INTRODUCTION: Severe cognitive impairment follows thyroid hormone deficiency during
the neonatal period. The role of nitric oxide (NO) in learning and memory has been widely …

Objective: Nitric oxide (NO) plays an important role both as a consequence and as a cause
of epileptic seizures. Regarding the central nervous system depressant effects of Achillea …

Background Cutaneous leishmaniasis (CL) topical treatments may have low efficacy, while
systemic treatments have adverse effects (AEs) and high cost. Since treatment options for …

Background The purpose of this study was to evaluate antileishmanial effects of ASA via NO
pathway in Leishmania major infected Balb/c mice. Moreover, toxicity and pathological …

Cutaneous leishmaniasis (CL), a dermatological parasitic infection caused by Leishmania
major and L. tropica. This disease is still one of the health problems in the tropical and sub …

Background: Current systemic treatments for cutaneous leishmaniasis are limited by their
toxicity, high cost, side effects and the emergence of drug resistance. New approaches …

Objective (s): To evaluate the effect of trinitroglycerin (TNG) as nitric oxide donor agent on
serum copper (Cu) and zinc (Zn) levels and liver enzymes in BALB/c mice infected with …