Acute graft-versus-host disease of the gut: considerations for the gastroenterologist

S Naymagon, L Naymagon, SY Wong, HM Ko… - Nature Reviews …, 2017 - nature.com
Haematopoietic stem cell transplantation (HSCT) is central to the management of many
haematological disorders. A frequent complication of HSCT is acute graft-versus-host …

Differential diagnosis of inflammatory bowel disease: imitations and complications

KB Gecse, S Vermeire - The lancet Gastroenterology & hepatology, 2018 - thelancet.com
Inflammatory bowel disease (IBD) is characterised by episodes of relapse and periods of
remission. However, the clinical features, such as abdominal pain, diarrhoea, and rectal …

[HTML][HTML] Immunosuppressive therapy after solid organ transplantation and the gut microbiota: Bidirectional interactions with clinical consequences

P Gabarre, C Loens, Y Tamzali, B Barrou… - American Journal of …, 2022 - Elsevier
Our understanding of the involvement of the gut microbiota (GM) in human health has
expanded exponentially over the last few decades, particularly in the fields of metabolism …

[HTML][HTML] Secondary causes of inflammatory bowel diseases

YA Ghouri, V Tahan, B Shen - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBD), conventionally consist of Crohn's disease (CD) and
ulcerative colitis. They occur in individuals with high risk genotype for the disease in the …

Vancomycin relieves mycophenolate mofetil–induced gastrointestinal toxicity by eliminating gut bacterial β-glucuronidase activity

MR Taylor, KL Flannigan, H Rahim, A Mohamud… - Science …, 2019 - science.org
Mycophenolate mofetil (MMF) is commonly prescribed and has proven advantages over
other immunosuppressive drugs. However, frequent gastrointestinal side effects through an …

[HTML][HTML] Gastrointestinal complications after kidney transplantation

R Gioco, D Corona, B Ekser, L Puzzo… - World Journal of …, 2020 - ncbi.nlm.nih.gov
Gastrointestinal complications are common after renal transplantation, and they have a wide
clinical spectrum, varying from diarrhoea to post-transplant inflammatory bowel disease …

Retracted: Efficacy and safety of mycophenolate mofetil in patients with active moderate‐to‐severe Graves' orbitopathy

X Ye, X Bo, X Hu, H Cui, B Lu, J Shao… - Clinical …, 2017 - Wiley Online Library
Context Graves' orbitopathy (GO) is a potentially sight‐threatening disease for which
currently available medical therapy is not reliably successful. Mycophenolate mofetil (MMF) …

Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate

JB Simpson, JJ Sekela, AL Graboski, VB Borlandelli… - Gut …, 2022 - Taylor & Francis
Mycophenolate mofetil (MMF) is an important immunosuppressant prodrug prescribed to
prevent organ transplant rejection and to treat autoimmune diseases. MMF usage, however …

An intact microbiota is required for the gastrointestinal toxicity of the immunosuppressant mycophenolate mofetil

KL Flannigan, MR Taylor, SK Pereira… - The Journal of Heart and …, 2018 - Elsevier
BACKGROUND Mycophenolate mofetil (MMF) is commonly prescribed after transplantation
and has major advantages over other immunosuppressive drugs, but frequent …

ECCO topical review on clinicopathological spectrum and differential diagnosis of inflammatory bowel disease

R Feakins, J Torres, P Borralho-Nunes… - Journal of Crohn's …, 2022 - academic.oup.com
Introduction Many diseases can imitate inflammatory bowel disease [IBD] clinically and
pathologically. This review outlines the differential diagnosis of IBD and discusses …