Upon antigenic stimulation, naïve CD4+ T cells differentiate into different subsets and
secrete various cytokines to exert biological effects. Th22 cells, a newly identified CD4+ T …

A critical role for IL-17, a cytokine produced by T helper 17 (Th17) cells, has been indicated
in the pathogenesis of chronic inflammatory and autoimmune diseases. A positive effect of …

Background Multiple sclerosis is a chronic immune-mediated disease of the brain and spinal
cord resulting in physical and cognitive impairment in young adults. It is hypothesized that a …

Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …

Abstract Interleukin-17 (IL-17) is a proinflammatory cytokine involved in chronic inflammation
occurring during the pathogenesis of allergy, malignancy, and autoimmune diseases such …

Multiple sclerosis (MS) is a common neurological disorder of putative autoimmune origin.
Clinical studies delineate abnormal expression of specific cytokines over the course of …

The role of T helper 17 (Th17) cells in auto-inflammatory neurological disorders such as
Multiple Sclerosis (MS), Alzheimer's disease (AD), Parkinson's disease (PD) and …

Abstract Interleukin-22 (IL22) is one of the members of IL10 family. Elevated levels of this
cytokine can be seen in diseases caused by T lymphocytes, such as Psoriasis, Rheumatoid …

Excessive levels of proinflammatory cytokines in the CNS are associated with reduced
serotonin (5‐HT) synthesis, a neurotransmitter with diverse immune effects. In this study, we …

Multiple sclerosis (MS) is an immunopathological disease that causes demyelination and
recurrent episodes of T cell-mediated immune attack in the central nervous system …