Expectations on mesenchymal stem cell (MSC) treatment are high, especially in the fields of
sepsis, transplant medicine, and autoimmune diseases. Various pre-clinical studies have …

Mesenchymal stromal cells (MSCs) have been extensively tested for the treatment of
numerous clinical conditions and have demonstrated good safety but mixed efficacy …

Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …

Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

Summary 2018 was the year of the first marketing authorization of an allogeneic stem cell
therapy by the European Medicines Agency. The authorization concerns the use of …

Mesenchymal stem cell transplantation (MSCT) has been recognized as a potent and
promising approach to achieve immunomodulation and tissue regeneration, but the …

Multipotent mesenchymal stem/stromal cells (MSCs) possess robust self-renewal
characteristics and the ability to differentiate into tissue-specific cells. Their therapeutic …

Lung macrophages (Mφs) are essential for pulmonary innate immunity and host defense
due to their dynamic polarization and phenotype shifts. Mesenchymal stromal cells (MSCs) …

Due to their anti-inflammatory, antiapoptotic, antimicrobial, and antifibrotic properties,
mesenchymal stromal cells (MSCs) have been considered a promising alternative for …

Rapid progress is occurring in understanding the mechanisms underlying mesenchymal
stromal cell (MSC)-based cell therapies (MSCT). However, the results of clinical trials, while …