Sleep and arousal: thalamocortical mechanisms

DA McCormick, T Bal - Annual review of neuroscience, 1997 - annualreviews.org
▪ Abstract Thalamocortical activity exhibits two distinct states:(a) synchronized rhythmic
activity in the form of delta, spindle, and other slow waves during EEG-synchronized sleep …

Molecular Structure and Physiological Functions of GABAB Receptors

B Bettler, K Kaupmann, J Mosbacher… - Physiological …, 2004 - journals.physiology.org
GABAB receptors are broadly expressed in the nervous system and have been implicated in
a wide variety of neurological and psychiatric disorders. The cloning of the first GABAB …

On the cellular and network bases of epileptic seizures

DA McCormick, D Contreras - Annual review of physiology, 2001 - annualreviews.org
▪ Abstract The highly interconnected networks of the mammalian forebrain can generate a
wide variety of synchronized activities, including those underlying epileptic seizures, which …

New GABA-targeting therapies for the treatment of seizures and epilepsy: I. Role of GABA as a modulator of seizure activity and recently approved medications acting …

E Perucca, M Bialer, HS White - CNS drugs, 2023 - Springer
Abstract γ-Aminobutyric acid (GABA) is the most prevalent inhibitory neurotransmitter in the
mammalian brain and has been found to play an important role in the pathogenesis or the …

The β Subunit of Voltage-Gated Ca2+ Channels

Z Buraei, J Yang - Physiological reviews, 2010 - journals.physiology.org
Calcium regulates a wide spectrum of physiological processes such as heartbeat, muscle
contraction, neuronal communication, hormone release, cell division, and gene …

Cellular mechanisms of a synchronized oscillation in the thalamus

M Krosigk von, T Bal, DA McCormick - Science, 1993 - science.org
Spindle waves are a prototypical example of synchronized oscillations, a common feature of
neuronal activity in thalamic and cortical systems in sleeping and waking animals …

Bridging the cleft at GABA synapses in the brain

I Mody, Y De Koninck, TS Otis, I Soltesz - Trends in neurosciences, 1994 - Elsevier
A fragile balance between excitation and inhibition maintains the normal functioning of the
CNS. The dominant inhibitory neurotransmitter of the mammalian brain is GABA, which acts …

Pathophysiological mechanisms of genetic absence epilepsy in the rat

L Danober, C Deransart, A Depaulis, M Vergnes… - Progress in …, 1998 - Elsevier
Generalized non-convulsive absence seizures are characterized by the occurrence of
synchronous and bilateral spike and wave discharges (SWDs) on the electroencephalogram …

Reproduced neuron-like excitability and bursting synchronization of memristive Josephson junctions loaded inductor

F Wu, H Meng, J Ma - Neural Networks, 2024 - Elsevier
Employing electronic component including memristor and Josephson junction to mimic
biological neuron or synapse has elicited intense research in recent years. Neurons …

Diversity of structure and function of GABAB receptors: a complexity of GABAB-mediated signaling

M Terunuma - Proceedings of the Japan Academy, Series B, 2018 - jstage.jst.go.jp
Abstract γ-aminobutyric acid type B (GABA B) receptors are broadly expressed in the
nervous system and play an important role in neuronal excitability. GABA B receptors are G …