Trehalose is a major circulatory sugar in the haemolymph of insects. It provides instant
energy and protection against stress. Trehalose metabolism is associated with insect growth …

Astrocytic metabolism has taken center stage. Interposed between the neuron and the
vasculature, astrocytes exert control over the fluxes of energy and building blocks required …

Here, we reveal an unanticipated role of the blood-brain barrier (BBB) in regulating complex
social behavior in ants. Using scRNA-seq, we find localization in the BBB of a key hormone …

Highlights•Drosophila glia share many properties with their mammalian
counterparts.•Different subpopulations of glia cells cooperate to support neuronal energy …

The need to protect neural tissue from toxins or other substances is as old as neural tissue
itself. Early recognition of this need has led to more than a century of investigation of the …

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized
by excessive deposition of fibrotic connective tissue in the lungs. Emerging evidence …

Neuronal function is highly energy demanding, requiring efficient transport of nutrients into
the central nervous system (CNS). Simultaneously the brain must be protected from the …

The accurate regulation of the microenvironment within the nervous system is one of the key
features characterizing complex organisms. To this end, neural tissue has to be physically …

Lipid droplets (LDs) are ubiquitous organelles that facilitate neutral lipid storage in cells,
including energy-dense triglycerides. They are found in all investigated metazoan embryos …

In the mid-1960s, bone morphogenetic proteins (BMPs) were first identified in the extracts of
bone to have the remarkable ability to induce heterotopic bone. When the Drosophila gene …