[HTML][HTML] A Novel method for the early detection of single circulating, metastatic and self-seeding cancer cells in orthotopic breast cancer mouse models

M Murad, Y Chen, J Iaria, A Fonseca Teixeira, HJ Zhu - Cells, 2024 - mdpi.com
Background: Metastasis is the main cause of cancer-related deaths, but efficient targeted
therapies against metastasis are still missing. Major gaps exist in our understanding of the …

HDAC1 and HDAC2 double knockout triggers cell apoptosis in advanced thyroid cancer

CL Lin, ML Tsai, CY Lin, KW Hsu, WS Hsieh… - International journal of …, 2019 - mdpi.com
Anaplastic thyroid carcinoma (ATC) and squamous thyroid carcinoma (STC) are both rare
and advanced thyroid malignancies with a very poor prognosis and an average median …

Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation

B Zhang, Q Hou, X Zhang, Y Ma, J Yuan, S Li… - Free Radical Biology …, 2023 - Elsevier
The impact of anesthetic management on the prognosis of patients with cancer undergoing
surgery is controversial. Circulating tumor cells (CTCs) play critical roles during cancer …

IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer

H Lu, J Ai, Y Zheng, W Zhou, L Zhang, J Zhu… - Cell Death & …, 2024 - nature.com
There is a paucity of comprehensive knowledge pertaining to the underlying mechanisms
leading to gefitinib resistance in individuals diagnosed NSCLC harboring EGFR-sensitive …

Human placental-derived stem cell therapy ameliorates experimental necrotizing enterocolitis

VG Weis, AC Deal, G Mekkey… - American Journal …, 2021 - journals.physiology.org
Necrotizing enterocolitis (NEC), a life-threatening intestinal disease, is becoming a larger
proportionate cause of morbidity and mortality in premature infants. To date, therapeutic …

ABL Genomic Editing Sufficiently Abolishes Oncogenesis of Human Chronic Myeloid Leukemia Cells In Vitro and In Vivo

SH Chen, YY Hsieh, HE Tzeng, CY Lin, KW Hsu… - Cancers, 2020 - mdpi.com
Chronic myelogenous leukemia (CML) is the most common type of leukemia in adults, and
more than 90% of CML patients harbor the abnormal Philadelphia chromosome (Ph) that …

HDAC1, 2 knock-out and HDACi induced cell apoptosis in imatinib-resistant K562 cells

SH Chen, JM Chow, YY Hsieh, CY Lin, KW Hsu… - International journal of …, 2019 - mdpi.com
Since imatinib (Glivec or Gleevec) has been used to target the BCR-ABL fusion protein,
chronic myeloid leukemia (CML) has become a manageable chronic disease with long-term …

Nicotinic acetylcholine receptor subtype alpha-9 mediates triple-negative breast cancers based on a spontaneous pulmonary metastasis mouse model

LC Huang, CL Lin, JZ Qiu, CY Lin, KW Hsu… - Frontiers in Cellular …, 2017 - frontiersin.org
Triple-negative breast cancer (TNBC) subtype is associated with poor prognosis and a high
risk of recurrence-related death in women. Despite the aggressiveness of TNBCs, targeted …

The application of non-invasive apoptosis detection sensor (NIADS) on histone deacetylation inhibitor (HDACi)-induced breast cancer cell death

KW Hsu, CY Huang, KW Tam, CY Lin… - International journal of …, 2018 - mdpi.com
Breast cancer is the most common malignancy in women and the second leading cause of
cancer death in women. Triple negative breast cancer (TNBC) subtype is a breast cancer …

α-Tocopherol succinate enhances pterostilbene anti-tumor activity in human breast cancer cells in vivo and in vitro

KW Tam, CT Ho, SH Tu, WJ Lee, CS Huang… - …, 2017 - pmc.ncbi.nlm.nih.gov
Vitamin E (Vit. E) is considered an essential dietary nutrient for humans and animals. An
enormous body of evidence indicates the biological and protective effects of Vit. E …