Over the past two decades, research has revealed that genetic factors shape the propensity
for aggressive, antisocial, and violent behavior. The best-documented gene implicated in …

With recent studies using genetic, epigenetic, and other molecular and neurochemical
approaches, a new era has begun in understanding pathophysiology of suicide. Emerging …

The positron-emitting radionuclide carbon-11 (11C, t1/2= 20.3 min) possesses the unique
potential for radiolabeling of any biological, naturally occurring, or synthetic organic …

The development of resistance by the antibiotics in the Gram-positive pathogenic bacteria
over the last twenty years and continuing today has created a need for new antibiotic …

Positron Emission Tomography has become a powerful scientific and clinical tool probing
biochemical processes in the human body. Their clinical applications have proven to be vital …

Abstract [11C] SL‐25.1188 [(S)‐5‐methoxymethyl‐3‐[6‐(4, 4, 4‐trifluorobutoxy)‐benzo [d]
isoxazol‐3‐yl]‐oxazolidin‐2‐one], an oxazolidinone derivative, was characterized in …

Biologically important processes in normal brain function and brain disease involve the
action of various protein-based receptors, ion channels, transporters and enzymes. The …

Type A and B monoamine oxidases (MAO-A,-B) mediate and modulate intracellular signal
pathways for survival or death of neuronal cells. MAO-A is associated with development of …

Alcohol dehydrogenases (ADHs) mediated biocatalytic asymmetric reduction of ketones
have been widely applied in the synthesis of optically active secondary alcohols with highly …

The inhibition of cerebral monoamine oxidases (MAOs) by cigarette smoke components
could participate to the tobacco addiction. However, the actual extent of this inhibition in vivo …