Targeting molecular pathways in cancer stem cells by natural bioactive compounds

D Cianciosi, A Varela-Lopez… - Pharmacological …, 2018 - Elsevier
Abstract Cancer Stem Cells (CSCs) or Tumor-Initiating Cells (TICs) are a small sub-
population of cells within the tumor, able to give chemio-and radio-resistance and cause the …

Natural products targeting the mitochondria in cancers

Y Yang, PY He, Y Zhang, N Li - Molecules, 2020 - mdpi.com
There are abundant sources of anticancer drugs in nature that have a broad prospect in
anticancer drug discovery. Natural compounds, with biological activities extracted from …

The revaluation of plant-derived terpenes to fight antibiotic-resistant infections

F Cappiello, MR Loffredo, C Del Plato, S Cammarone… - Antibiotics, 2020 - mdpi.com
The discovery of antibiotics has revolutionized the medicine and treatment of microbial
infections. However, the current scenario has highlighted the difficulties in marketing new …

A unique high-diversity natural product collection as a reservoir of new therapeutic leads

F Ghirga, D Quaglio, M Mori, S Cammarone… - Organic Chemistry …, 2021 - pubs.rsc.org
Plants represent a rich source of structurally diverse secondary metabolites, which can be
exploited in the development of new clinically important compounds. Indeed, due to their …

Current report of natural product development against breast cancer stem cells

A Hermawan, H Putri - The international journal of biochemistry & cell …, 2018 - Elsevier
Chemotherapeutic agents are commonly used as neoadjuvant for breast cancer therapy.
However, there is evidence of treatment failure for most of patients due to acquired …

Complementary and alternative medicine and breast cancer

R Subramani, R Lakshmanaswamy - Progress in molecular biology and …, 2017 - Elsevier
Complementary and alternative medicine (CAM) has been in use among cancer patients for
a long time. There are several types of CAM that are practiced in various parts of the world …

Triterpene Acid (3-O-p-Coumaroyltormentic Acid) Isolated From Aronia Extracts Inhibits Breast Cancer Stem Cell Formation through Downregulation of c-Myc …

HS Choi, SL Kim, JH Kim, HY Deng, BS Yun… - International journal of …, 2018 - mdpi.com
Cancer stem cells (CSCs) are drug-resistant and radiation-resistant cancer cells that are
responsible for tumor progression and maintenance, cancer recurrence, and metastasis …

Nano-delivery system targeting to cancer stem cell cluster of differentiation biomarkers

A Mokhtarzadeh, S Hassanpour, ZF Vahid… - Journal of Controlled …, 2017 - Elsevier
Cancer stem cells (CSCs) are one of the most important origins of cancer progression and
metastasis. CSCs have unique self-renewal properties and diverse cell membrane receptors …

Unveiling the pharmacological potential of plant triterpenoids in breast cancer management: An updated review

SH Aly, AMM Elbadry, AS Doghish… - Naunyn-Schmiedeberg's …, 2024 - Springer
Breast cancer is the most prevalent type of cancer, the fifth leading cause of cancer-related
deaths, and the second leading cause of cancer deaths among women globally. Recent …

[HTML][HTML] 22β-hydroxytingenone induces apoptosis and suppresses invasiveness of melanoma cells by inhibiting MMP-9 activity and MAPK signaling

ESP Aranha, AJ de Sousa Portilho, LB de Sousa… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance 22β-hydroxytingenone (22-HTG) is a
quinonemethide triterpene isolated from Salacia impressifolia (Miers) AC Smith (family …