From inert storage to biological activity—in search of identity for oxidized cholesteryl esters

A Gonen, YI Miller - Frontiers in endocrinology, 2020 - frontiersin.org
Esterification of cholesterol is a universal mechanism to store and transport large quantities
of cholesterol between organs and tissues and to avoid toxicity of the excess of cellular …

Quality control and removal of technical variation of NMR metabolic biomarker data in~ 120,000 UK Biobank participants

SC Ritchie, P Surendran, S Karthikeyan, SA Lambert… - Scientific data, 2023 - nature.com
Metabolic biomarker data quantified by nuclear magnetic resonance (NMR) spectroscopy in
approximately 121,000 UK Biobank participants has recently been released as a community …

Lipidomics study of plasma from patients suggest that ALS and PLS are part of a continuum of motor neuron disorders

E Area-Gomez, D Larrea, T Yun, Y Xu, J Hupf… - Scientific Reports, 2021 - nature.com
Motor neuron disorders (MND) include a group of pathologies that affect upper and/or lower
motor neurons. Among them, amyotrophic lateral sclerosis (ALS) is characterized by …

[HTML][HTML] The Impact of Maternal Chronic Inflammatory Conditions on Breast Milk Composition: Possible Influence on Offspring Metabolic Programming

G Arenas, MJ Barrera, S Contreras-Duarte - Nutrients, 2025 - mdpi.com
Breastfeeding is the best way to provide newborns with crucial nutrients and produce a
unique bond between mother and child. Breast milk is rich in nutritious and non-nutritive …

Longitudinal changes in circulating metabolites and lipoproteins after breast cancer treatment

GF Giskeødegård, TS Madssen, M Sangermani… - Frontiers in …, 2022 - frontiersin.org
The multimodal treatment of breast cancer may induce long term effects on the metabolic
profile and increase the risk of future cardiovascular disease. In this study, we characterized …

Monobutyrin reduces liver cholesterol and improves intestinal barrier function in rats fed high-fat diets

TD Nguyen, O Prykhodko, FF Hållenius, M Nyman - Nutrients, 2019 - mdpi.com
Butyric acid has been shown to reduce high-fat diet-related metabolic disturbances and to
improve intestinal barrier function due to its potent anti-inflammatory capacity. This study …

[HTML][HTML] CXCL5 inhibits excessive oxidative stress by regulating white adipocyte differentiation

D Lee, KH Lee, DW Kim, S Yoon, JY Cho - Redox Biology, 2022 - Elsevier
Chemokines have been well-documented as a major factor in immune cell migration and the
regulation of immune responses. However, recent studies have reported that chemokines …

Flexible Microtube Plasma for the Consecutive-Ionization of Cholesterol in Nano-Electrospray Mass Spectrometry

D Foest, A Knodel, R Ahrends, C Coman… - Analytical …, 2023 - ACS Publications
Electrospray ionization mass spectrometry (ESI-MS) is an established method for the
identification of biomarkers. By nano-ESI (nESI), the polar molecular fraction of complex …

Evaluating pathological levels of intracellular cholesterol through Raman and surface-enhanced Raman spectroscopies

E Baria, C Dallari, F Mattii, FS Pavone, C Credi… - Scientific Reports, 2024 - nature.com
Versatile methods for the quantification of intracellular cholesterol are essential for
understanding cellular physiology and for diagnosing disorders linked to cholesterol …

Differential expression of lipid metabolic genes in hypercholesterolemic rabbit placenta predisposes the offspring to develop atherosclerosis in early adulthood

VS Jayalekshmi, VS Jaikumar, P Mehra… - Life Sciences, 2023 - Elsevier
Aims Maternal hypercholesterolemia (MHC) is a pathological condition that may cause
atherosclerosis in the adulthood of the offspring. The study aims to identify the role of in …