Brain edema leading to an expansion of brain volume has a crucial impact on morbidity and
mortality following traumatic brain injury (TBI) as it increases intracranial pressure, impairs …

Aquaporin-4 (AQP4) is the major water channel expressed in brain perivascular astrocyte
processes. Although the role of AQP4 in brain edema has been extensively investigated …

The association of pericytes (PCs) to newly formed blood vessels has been suggested to
regulate endothelial cell (EC) proliferation, survival, migration, differentiation, and vascular …

ABSTRACT Aquaporin‐4 (AQP4) is the major water channel in the brain, expressed
predominantly in astroglial cell membranes. Initial studies in AQP4‐deficient mice showed …

The water channel AQP4 is concentrated in perivascular and subpial membrane domains of
brain astrocytes. These membranes form the interface between the neuropil and …

Aquaporin-4 (AQP4) is a highly conserved water channel protein. In rats, AQP4 is expressed
in astrocyte foot processes and is important in brain water homeostasis. AQP4 expression …

A calcein fluorescence quenching method was applied to measure osmotic water
permeability in highly differentiated primary cultures of brain astrocytes from wild-type and …

The astroglial water channel aquaporin-4 (AQP4) facilitates water movement into and out of
brain parenchyma. To investigate the role of AQP4 in meningitis-induced brain edema …

Cerebral water accumulation was studied during induction of brain edema in dystrophin-null
transgenic mice (mdx-β geo) and control mice. Immunofluorescence and immunoelectron …

In this review, we have tried to summarize most available data dealing with the aquaporin
(AQP) family of water channels in the CNS. Two aquaporins have been identified so far in …