Selective breeding for high voluntary exercise in mice increases maximal (V̇O2, max) but not basal metabolic rate

NE Schwartz, MP McNamara… - Journal of …, 2023 - journals.biologists.com
In general, sustained high rates of physical activity require a high maximal aerobic capacity
(V̇ O 2, max), which may also necessitate a high basal aerobic metabolism (BMR), given …

Host-specific effects of Eubacterium species on Rg3-mediated modulation of osteosarcopenia in a genetically diverse mouse population

S Hong, BN Nguyen, H Min, HY Youn, S Choi… - Microbiome, 2024 - Springer
Osteosarcopenia, characterized by the simultaneous loss of bone and muscle mass, is a
serious health problem in the aging population. This study investigated the interplay …

Effects of broad-spectrum antibiotic treatment or germ-free status on endurance performance and exercise adaptations in mice

NT Hutchinson, SS Wang, J Dokhanchi… - … and science in …, 2022 - pmc.ncbi.nlm.nih.gov
Purpose: Endurance exercise alters the gut microbiome independently of diet. The extent to
which gut microbes are responsible for physiologic adaptations to exercise training is …

[HTML][HTML] Effects of food restriction on voluntary wheel-running behavior and body mass in selectively bred High Runner lines of mice

Z Thompson, IAT Fonseca, W Acosta, L Idarraga… - Physiology & …, 2024 - Elsevier
Food restriction can have profound effects on various aspects of behavior, physiology, and
morphology. Such effects might be amplified in animals that are highly active, given that …

[HTML][HTML] Maternal exercise opportunity before, during, and after pregnancy alters maternal care behavior and offspring development and survival, but has few effects …

NE Schwartz, MP Schmill, MD Cadney, AA Castro… - Physiology & …, 2025 - Elsevier
Early-life experiences, especially during critical periods of development and growth, can
have long-lasting effects on adult phenotypes. Parents are a crucial part of the offspring …

Weanling gut microbiota composition of a mouse model selectively bred for high voluntary wheel-running behavior

MP McNamara, EM Venable… - Journal of …, 2023 - journals.biologists.com
We compared the fecal microbial community composition and diversity of four replicate lines
of mice selectively bred for high wheel-running activity over 81 generations (HR lines) and …

Microbiota influence on behavior: Integrative analysis of serotonin metabolism and behavioral profile in germ‐free mice

L Roussin, E Gry, M Macaron, S Ribes… - The FASEB …, 2024 - Wiley Online Library
Previous studies on germ‐free (GF) animals have described altered anxiety‐like and social
behaviors together with dysregulations in brain serotonin (5‐HT) metabolism. Alterations in …

[PDF][PDF] Microbiota Mediate Enhanced Exercise Capacity Induced by Exercise Training

RA Dowden, PJ Wisniewski, CR Longoria… - Medicine & Science …, 2023 - researchgate.net
Microbiota Mediate Enhanced Exercise Capacity Induced by Exercise Training Page 1 Microbiota
Mediate Enhanced Exercise Capacity Induced by Exercise Training ROBERT A. DOWDEN1,2,3 …

Limosilactobacillus Fermentun ZS09 Can Improve Antibiotic-Induced Motor Dysfunction in Mice by Regulating the Brain–Gut Functions

Y Yang, Y Zhao, H Lei, X Tan - Journal of Inflammation Research, 2024 - Taylor & Francis
Purpose When consumed in appropriate quantities, probiotics, which are live
microorganisms, are good for health. In this study, a mouse model of antibiotic-induced …

Identifying and elucidating the gut microbiota-brown adipose tissue axis

CR Longoria - 2023 - search.proquest.com
The gut microbiota and their associated metabolites are influential regulators of host
phenotype and health. Deviations from a host's normal gut microbiota, or dysbiosis, can alter …