[HTML][HTML] Recent advances in sensing the inter-biomolecular interactions at the nanoscale–A comprehensive review of AFM-based force spectroscopy

A Lostao, KS Lim, MC Pallarés, A Ptak… - International journal of …, 2023 - Elsevier
Biomolecular interactions underpin most processes inside the cell. Hence, a precise and
quantitative understanding of molecular association and dissociation events is crucial, not …

Atomic force microscopy to elicit conformational transitions of ferredoxin-dependent flavin thioredoxin reductases

C Marcuello, GA Frempong, M Balsera, M Medina… - Antioxidants, 2021 - mdpi.com
Flavin and redox-active disulfide domains of ferredoxin-dependent flavin thioredoxin
reductase (FFTR) homodimers should pivot between flavin-oxidizing (FO) and flavin …

Nanomechanical Study of Enzyme: Coenzyme Complexes: Bipartite Sites in Plastidic Ferredoxin-NADP+ Reductase for the Interaction with NADP+

S Pérez-Domínguez, S Caballero-Mancebo… - Antioxidants, 2022 - mdpi.com
Plastidic ferredoxin-NADP+ reductase (FNR) transfers two electrons from two ferredoxin or
flavodoxin molecules to NADP+, generating NADPH. The forces holding the Anabaena …

HDX-MS reveals substrate-dependent, localized EX1 conformational dynamics in the retaining GT-B glycosyltransferase, MshA

R Karki, JT Hennek, W Chen, PA Frantom - Biochemistry, 2023 - ACS Publications
Glycosyltransferases (GTs) are well-characterized with respect to static 3D structures and
molecular dynamics simulations, but there is a lack of reports on in-solution dynamics on …

Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation

T Xu, Q Gan, Q Liu, R Chen, X Zhen… - … Section D: Structural …, 2022 - journals.iucr.org
Elaiophylin (Ela), a unique 16-membered symmetric macrodiolide antibiotic, displays broad
biological activity. Two rare 2-deoxy-l-fucose moieties at the ends of Ela are critical for its …