The gasdermins are a family of recently identified pore-forming effector proteins that cause
membrane permeabilization and pyroptosis, a lytic pro-inflammatory type of cell death …

In response to a wide range of stimulations, host cells activate pyroptosis, a kind of
inflammatory cell death which is provoked by the cytosolic sensing of danger signals and …

Pyroptosis was long regarded as caspase-1-mediated monocyte death in response to
certain bacterial insults. Caspase-1 is activated upon various infectious and immunological …

The gasdermin (GSDM) family, a novel group of structure-related proteins, consists of
GSDMA, GSDMB, GSDMC, GSDMD, GSDME/DNFA5, and PVJK/GSDMF. GSDMs possess …

The Gasdermin (GSDM) family consists of Gasdermin A (GSDMA), Gasdermin B (GSDMB),
Gasdermin C (GSDMC), Gasdermin D (GSDMD), Gasdermin E (GSDME) and Pejvakin …

Since the identification and characterization of gasdermin (GSDM) D as the main effector of
inflammatory regulated cell death (or pyroptosis), literature on the GSDM family of pore …

Since their discovery, members of the gasdermin (GSDM) family of proteins have been firmly
established as executors of pyroptosis, with the N-terminal fragment of most GSDMs capable …

Noise overexposure causes oxidative stress, leading to auditory hair cell damage. Adaptive
peroxisome proliferation involving pejvakin, a peroxisome-associated protein from the …

Gasdermins (GSDMs) belong to a protein superfamily that is found only in vertebrates and
consists of GSDMA, GSDMB, GSDMC, GSDMD, DFNA5 (aka GSDME) and DFNB59 (aka …

Pyroptosis is a type of lytic programmed cell death triggered by various inflammasomes that
sense danger signals. Pyroptosis has recently attracted great attention owing to its …