With an expanding elderly population and median rectal cancer detection age of 70 years,
the prevalence of rectal cancer in elderly patients is increasing. Management is based on …

Liver metastasis is the most common site of colorectal cancer (CRC) metastasis.
Approximately half of all colorectal cancer patients will develop liver metastases. Although …

Purpose The optimal chemotherapy regimen administered concurrently with preoperative
radiation therapy (RT) for patients with rectal cancer is unknown. National Surgical Adjuvant …

Background In stage III colon cancer, oxaliplatin/5-fluorouracil (5-FU)-based adjuvant
chemotherapy (FOLFOX) improves disease-free survival (DFS) and overall survival (OS). In …

Background There is no consensus on the role of postoperative chemotherapy in patients
with rectal cancer who have received preoperative radio (chemo) therapy. Materials and …

For patients with high-risk stage II or stage III colon cancer, adjuvant chemotherapy with
fluoropyrimidine monotherapy reduces the risk of recurrence and death by approximately 20 …

Simple Summary The management of rectal cancer has become increasingly more complex.
Over the recent year, the use of chemotherapy and radiation before surgical intervention has …

Background Outcome of intermediate risk rectal cancer may be improved by the addition of
oxaliplatin during 5-fluoruracil concomitant neoadjuvant chemoradiotherapy. The purpose of …

In rectal cancer treatment, attention has focused on the local primary tumour and the
regional tumour cell deposits to diminish the risk of a loco-regional recurrence. Several large …

Introduction This document is a summary of the French Intergroup guidelines regarding the
management of rectal adenocarcinoma published in February 2016. Method This …