Candida albicans, a major human fungal pathogen

J Kim, P Sudbery - The journal of microbiology, 2011 - Springer
Candida albicans is the most common human fungal pathogen (Beck-Sague and Jarvis,
1993). It is normally a harmless commensal organism. However, it is a opportunistic …

Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

JR Naglik, SJ Challacombe, B Hube - Microbiology and molecular …, 2003 - Am Soc Microbiol
Candida albicans is the most common fungal pathogen of humans and has developed an
extensive repertoire of putative virulence mechanisms that allows successful colonization …

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

G Butler, MD Rasmussen, MF Lin, MAS Santos… - Nature, 2009 - nature.com
Candida species are the most common cause of opportunistic fungal infection worldwide.
Here we report the genome sequences of six Candida species and compare these and …

The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

O Reuß, Å Vik, R Kolter, J Morschhäuser - Gene, 2004 - Elsevier
The construction of Candida albicans mutants by targeted gene disruption usually depends
on the use of nutritional markers for the selection of prototrophic transformants from …

Candida albicans: A molecular revolution built on lessons from budding yeast

J Berman, PE Sudbery - Nature Reviews Genetics, 2002 - nature.com
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, in immunocompromised patients …

Microbe Profile: Candida albicans: a shape-changing, opportunistic pathogenic fungus of humans

NAR Gow, B Yadav - Microbiology, 2017 - microbiologyresearch.org
Candida albicans is normally a harmless commensal of human beings, but it can cause
superficial infections of the mucosa (oral/vaginal thrush) in healthy individuals and (rarely) …

Large‐scale essential gene identification in Candida albicans and applications to antifungal drug discovery

T Roemer, B Jiang, J Davison, T Ketela… - Molecular …, 2003 - Wiley Online Library
Candida albicans is the primary fungal pathogen of humans. Despite the need for novel
drugs to combat fungal infections [Sobel, JD (2000) Clin Infectious Dis 30: 652], antifungal …

Most azole resistance mutations in the Candida albicans drug target confer cross-resistance without intrinsic fitness cost

C Bédard, I Gagnon-Arsenault, J Boisvert, S Plante… - Nature …, 2024 - nature.com
Azole antifungals are the main drugs used to treat fungal infections. Amino acid substitutions
in the drug target Erg11 (Cyp51) are a common resistance mechanism in pathogenic yeasts …

[HTML][HTML] Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating …

VR Stoldt, A Sonneborn, CE Leuker, JF Ernst - The EMBO journal, 1997 - embopress.org
We identified a gene of the fungal pathogen Candida albicans, designated EFG1, whose
high‐level expression stimulates pseudohyphal morphogenesis in the yeast …

The evolution of sex: a perspective from the fungal kingdom

SC Lee, M Ni, W Li, C Shertz… - … and molecular biology …, 2010 - Am Soc Microbiol
Sex is shrouded in mystery. Not only does it preferentially occur in the dark for both fungi
and many animals, but evolutionary biologists continue to debate its benefits given costs in …