Nucleic acids are important biomarkers related to diseases of cancer, infectious, and genetic
disorders. As a kind of indicator, gold nanoparticles (AuNPs) can generate colored signals …

Modern optical detection technology plays a critical role in current clinical detection due to
its high sensitivity and accuracy. However, higher requirements such as extremely high …

Extracellular vesicles (EVs) are emerging as one of the many new and promising
biomarkers for liquid biopsy of cancer due to their loading capability of some specific …

Since the advent of its theoretical discovery more than 30 years ago, DNA nanotechnology
has been used in a plethora of diverse applications in both the fundamental and applied …

We established four-point guidelines for the sequence design of hairpin monomers in
hybridization chain reaction (HCR). This enabled greater flexibility to customize specific …

The advent of modern biomedical science has led to various accomplishments such as the
early detection of genetic disorders. To pursue further advancement in this field, the …

The combination of high selectivity of aptamer with the peroxidase-mimicking property of
DNAzyme has presented considerable opportunities for designing colorimetric aptasensor …

A versatile and ultrasensitive colorimetric detection platform has been developed based on
the hybridization chain reaction (HCR)-triggered enzyme cascade amplification in this work …

A novel and simple colorimetric biosensor was developed by combining the unique optical
properties of unmodified gold nanorods (AuNRs) with the amplification strategy of …

A genomic DNA-based colorimetric assay is described for the detection of the early growth
factor receptor (EGFR) mutation, which is the protruding reason for non-small cell lung …