Redox homeostasis is an essential requirement of the biological systems for performing
various normal cellular functions including cellular growth, differentiation, senescence …

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the
United States with a median survival of< 6 mo and a dismal 5-yr survival rate of 3%–5%. The …

Pancreatic ductal adenocarcinoma is an aggressive and devastating disease, which is
characterized by invasiveness, rapid progression and profound resistance to treatment …

Objectives: Pancreatic cancer has a very poor prognosis, largely due to its propensity for
early local and distant spread. Histopathologically, most pancreatic cancers are …

Background: The precise details of pancreatic ductal adenocarcinoma (PDAC)
pathogenesis are still insufficiently known, requiring the use of higthroughput methods …

The molecular basis of pancreatic cancer is not understood. Previous attempts to determine
the specific genes expressed in pancreatic cancer have been hampered by similarities …

Pancreatic cancer is the fifth leading cause of cancer death in the United States. We used
cDNA microarrays to analyze global gene expression patterns in 14 pancreatic cancer cell …

Cancer is a highly variable disease with multiple heterogeneous genetic and epigenetic
changes. Functional studies are essential to understanding the complexity and …

The median survival for patients with locally advanced pancreatic cancer treated with
gemcitabine and radiation is approximately 1 year. To develop improved treatment, we have …

The Rad51 recombinase is an essential factor for homologous recombination and the repair
of DNA double strand breaks, binding transiently to both single stranded and double …