Cancer is a condition where the body cells multiply in an uncontrollable manner.
Chemoprevention of cancer is a broad term that describes the involvement of external …

Ethnopharmacological relevance Ruta genus is constituted by ten species, of which the
most commonly described are R. chalepensis and R. graveolens. Ruta plants are perennial …

Graveoline exhibits various biological activities. However, only limited studies have focused
on its hepatoprotective properties. This study evaluated the anti-inflammatory and …

Aluminum (Al), as a common environmental pollutant, causes osteoblast (OB) dysfunction
and then leads to Al-related bone diseases (ARBD). One of the mechanisms of ARBD is …

Reported herein is the fluorination of α-imino gold carbenes, generated in situ from
azidoalkynes, to access substituted C3-fluorinated quinolones and indoles. The …

The genus Ruta in the family Rutaceae includes about 40 species, such as the well-known
plants R. graveolens L.(common rue) or R. chalepensis L.(fringed rue), but also much lesser …

4-Quinolones are the structural elements of many pharmaceutically active compounds.
Although several approaches are known for their synthesis, the introduction of an aryl ring in …

Skin cancer, a prevalent malignancy worldwide, poses significant health concerns owing to
its increasing incidence. Autophagy, a natural cellular process, is a pivotal event in skin …

An efficient and chemoselective transformation of β-amido ynones to 3-acyl-substituted
quinolones 2 and 3-H-quinolones 4 has been developed. In this reaction, β-cyclic amido …

In the present study, we investigated the anti-cancer effect of various potencies of Ruta
graveolens (Ruta) on COLO-205 cell line, as evidenced by cytotoxicity, migration …