Objective To compare the risk for all cause and overdose mortality in people with opioid
dependence during and after substitution treatment with methadone or buprenorphine and …

Background Retention in opioid substitution (OST) treatment is associated with substantial
reductions in all cause and overdose mortality. This systematic review aims to identify both …

We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to address …

Opioid use disorder (OUD) is associated with a high risk of premature death. Medication-
assisted treatment (MAT) is the primary treatment for opioid dependence. We …

Background. Human immunodeficiency virus (HIV)–infected people who inject drugs (PWID)
frequently encounter barriers accessing and remaining on antiretroviral therapy (ART) …

Aims To estimate whether opioid substitution treatment (OST) with buprenorphine or
methadone is associated with a greater reduction in the risk of all‐cause mortality (ACM) …

Introduction A recent surge in HIV outbreaks, driven by the opioid and stimulant use crises,
has destabilized our progress toward targets set forth by Ending the HIV Epidemic: A Plan …

Background Pharmacological treatments for opioid use disorder are essential, life-saving
medications, yet successful induction of them and long-term retention on them is limited in …

Design: Systematic review and meta-analysis of cohorts of people with OUD involving illicit
opioids with data on all-cause or overdose-specific mortality. Setting and Participants: Of …

Background HIV incidence is increasing in eastern Europe and central Asia, primarily driven
by injecting drug use. Coverage of antiretroviral therapy (ART) and opioid agonist therapy …