Iron Oxide Nanoparticles as T1 Contrast Agents for Magnetic Resonance Imaging: Fundamentals, Challenges, Applications, and Prospectives

M Jeon, MV Halbert, ZR Stephen… - Advanced Materials, 2021 - Wiley Online Library
Gadolinium‐based chelates are a mainstay of contrast agents for magnetic resonance
imaging (MRI) in the clinic. However, their toxicity elicits severe side effects and the Food …

Structure–relaxivity relationships of magnetic nanoparticles for magnetic resonance imaging

Z Zhou, L Yang, J Gao, X Chen - Advanced Materials, 2019 - Wiley Online Library
Magnetic nanoparticles (MNPs) have been extensively explored as magnetic resonance
imaging (MRI) contrast agents. With the increasing complexity in the structure of modern …

Iron oxide based nanoparticles for multimodal imaging and magnetoresponsive therapy

N Lee, D Yoo, D Ling, MH Cho, T Hyeon… - Chemical …, 2015 - ACS Publications
Magnetic nanoparticles have received tremendous attention in diverse fields because of
their unique nanoscale physicochemical properties and the potential for a wide range of …

Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

D Ni, W Bu, EB Ehlerding, W Cai, J Shi - Chemical Society Reviews, 2017 - pubs.rsc.org
Magnetic resonance imaging (MRI) is a highly valuable non-invasive imaging tool owing to
its exquisite soft tissue contrast, high spatial resolution, lack of ionizing radiation, and wide …

Magnetic nanoparticles: surface effects and properties related to biomedicine applications

B Issa, IM Obaidat, BA Albiss, Y Haik - International journal of molecular …, 2013 - mdpi.com
Due to finite size effects, such as the high surface-to-volume ratio and different crystal
structures, magnetic nanoparticles are found to exhibit interesting and considerably different …

Superparamagnetic nanoparticles for biomedical applications

Y Xiao, J Du - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
In this review, we summarized recent advances in the development and biological
applications of polymeric nanoparticles embedded with superparamagnetic iron oxide …

[HTML][HTML] Recent advances in engineering iron oxide nanoparticles for effective magnetic resonance imaging

Z Zhao, M Li, J Zeng, L Huo, K Liu, R Wei, K Ni, J Gao - Bioactive Materials, 2022 - Elsevier
Iron oxide nanoparticle (IONP) with unique magnetic property and high biocompatibility
have been widely used as magnetic resonance imaging (MRI) contrast agent (CA) for long …

Large-Scale Synthesis of Uniform and Extremely Small-Sized Iron Oxide Nanoparticles for High-Resolution T1 Magnetic Resonance Imaging Contrast Agents

BH Kim, N Lee, H Kim, K An, YI Park… - Journal of the …, 2011 - ACS Publications
Uniform and extremely small-sized iron oxide nanoparticles (ESIONs) of< 4 nm were
synthesized via the thermal decomposition of iron–oleate complex in the presence of oleyl …

Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications

S Laurent, D Forge, M Port, A Roch, C Robic… - Chemical …, 2008 - ACS Publications
In the past decade, the synthesis of superparamagnetic nanoparticles has been intensively
developed not only for its fundamental scientific interest but also for many technological …

Design of iron oxide-based nanoparticles for MRI and magnetic hyperthermia

C Blanco-Andujar, A Walter, G Cotin, C Bordeianu… - …, 2016 - Taylor & Francis
Iron oxide nanoparticles are widely used for biological applications thanks to their
outstanding balance between magnetic properties, surface-to-volume ratio suitable for …