Estrogens, steroid hormones critically involved in reproductive processes of vertebrates,
signal primarily through their intracellular estrogen receptors (ERs). The ERs belong to a …

The advent of new genomic techniques has raised expectations that central questions of
mixture toxicology such as for mechanisms of low dose interactions can now be answered …

Estrogens work by binding to and activating specific estrogen receptors (ERs). Although
mammals have two major nuclear ER subtypes (ERα and ERβ), three subtypes have been …

MicroRNAs (miRNAs) which regulate gene expression stability displayed an aberrant
expression profile in ectopic endometrium (ECE) as compared to eutopic (EUE) and normal …

The aryl hydrocarbon receptor (AhR) and the estrogen receptor (ER) are ligand-activated
transcription factors, both of which can be activated by environmental pollutants. The AhR …

Estrogens are important for bi-directional neuroendocrine-immune interaction. They act via
nuclear estrogen receptors (ERα and ERβ) and/or G-protein coupled receptor-GPR30. We …

Seminiferous tubular atrophy may involve indirectly the disruption of estrogen receptor-α
(ESR1) function in efferent ductules of the testis. ESR1 helps to maintain fluid resorption by …

Endocrine-disrupting chemicals (EDCs) comprise a group of environmental contaminants
that can disturb the normal functioning of the hormonal system, can cause adverse effects in …

There is much concern about the increasing presence in the environment of synthetic
chemicals that are able to disrupt the endocrine system. Among these compounds, 4 …

To assess the adverse toxicological effects of steroid hormones on western mosquitofish
(Gambusia affinis), 180 adult females were exposed to individual or binary combinations of …