Connectomics of bipolar disorder: a critical review, and evidence for dynamic instabilities within interoceptive networks

A Perry, G Roberts, PB Mitchell, M Breakspear - Molecular psychiatry, 2019 - nature.com
The notion that specific cognitive and emotional processes arise from functionally distinct
brain regions has lately shifted toward a connectivity-based approach that emphasizes the …

Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

DP Hibar, LT Westlye, NT Doan, N Jahanshad… - Molecular …, 2018 - nature.com
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well
understood. Structural brain differences have been associated with BD, but results from …

Functional neuroanatomy of response inhibition in bipolar disorders–combined voxel based and cognitive performance meta-analysis

T Hajek, M Alda, E Hajek, J Ivanoff - Journal of psychiatric research, 2013 - Elsevier
Objectives Impaired response inhibition underlies symptoms and altered functioning in
patients with bipolar disorders (BD). The interpretation of fMRI studies requires an accurate …

The contribution of geometry to the human connectome

JA Roberts, A Perry, AR Lord, G Roberts, PB Mitchell… - Neuroimage, 2016 - Elsevier
The human connectome is a topologically complex, spatially embedded network. While its
topological properties have been richly characterized, the constraints imposed by its spatial …

Default-mode and fronto-parietal network connectivity during rest distinguishes asymptomatic patients with bipolar disorder and major depressive disorder

S Rai, KR Griffiths, IA Breukelaar, AR Barreiros… - Translational …, 2021 - nature.com
Bipolar disorder (BD) is commonly misdiagnosed as major depressive disorder (MDD). This
is understandable, as depression often precedes mania and is otherwise indistinguishable …

Happy facial expressions impair inhibitory control with respect to fearful facial expressions but only when task-relevant.

C Mancini, L Falciati, C Maioli, G Mirabella - Emotion, 2022 - psycnet.apa.org
The ability to generate appropriate responses, especially in social contexts, requires
integrating emotional information with ongoing cognitive processes. In particular, inhibitory …

Dwelling quietly in the rich club: brain network determinants of slow cortical fluctuations

LL Gollo, A Zalesky, RM Hutchison… - … of the Royal …, 2015 - royalsocietypublishing.org
For more than a century, cerebral cartography has been driven by investigations of structural
and morphological properties of the brain across spatial scales and the temporal/functional …

Functional dysconnection of the inferior frontal gyrus in young people with bipolar disorder or at genetic high risk

G Roberts, A Lord, A Frankland, A Wright, P Lau… - Biological …, 2017 - Elsevier
Background Bipolar disorder (BD) is characterized by a dysregulation of affect and impaired
integration of emotion with cognition. These traits are also expressed in probands at high …

[HTML][HTML] Segregating domain-general from emotional context-specific inhibitory control systems-ventral striatum and orbitofrontal cortex serve as emotion-cognition …

Q Zhuang, L Xu, F Zhou, S Yao, X Zheng, X Zhou, J Li… - Neuroimage, 2021 - Elsevier
Inhibitory control hierarchically regulates cognitive and emotional systems in the service of
adaptive goal-directed behavior across changing task demands and environments. While …

[HTML][HTML] Fronto-limbic dysconnectivity leads to impaired brain network controllability in young people with bipolar disorder and those at high genetic risk

J Jeganathan, A Perry, DS Bassett, G Roberts… - NeuroImage: Clinical, 2018 - Elsevier
Recent investigations have used diffusion-weighted imaging to reveal disturbances in the
neurocircuitry that underlie cognitive-emotional control in bipolar disorder (BD) and in …