Advancement in leishmaniasis diagnosis and therapeutics: An update

D Kumari, S Perveen, R Sharma, K Singh - European Journal of …, 2021 - Elsevier
Leishmaniasis is regarded as a neglected tropical disease by World Health Organization
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …

Leishmania tarentolae: a vaccine platform to target dendritic cells and a surrogate pathogen for next generation vaccine research in leishmaniases and viral …

C Bandi, JA Mendoza-Roldan, D Otranto, A Alvaro… - Parasites & …, 2023 - Springer
Parasites of the genus Leishmania are unusual unicellular microorganisms in that they are
characterized by the capability to subvert in their favor the immune response of mammalian …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

Leishmania tarentolae: Taxonomic classification and its application as a promising biotechnological expression host

S Klatt, L Simpson, DA Maslov… - PLoS neglected tropical …, 2019 - journals.plos.org
In this review, we summarize the current knowledge concerning the eukaryotic protozoan
parasite Leishmania tarentolae, with a main focus on its potential for biotechnological …

Peptides to tackle leishmaniasis: Current status and future directions

AA Robles-Loaiza, EA Pinos-Tamayo… - International journal of …, 2021 - mdpi.com
Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by
the pharmaceutical industry. These molecules are currently being used in the development …

Development of Various Leishmania (Sauroleishmania) tarentolae Strains in Three Phlebotomus Species

L Ticha, B Kykalova, J Sadlova, M Gramiccia… - Microorganisms, 2021 - mdpi.com
Leishmania (Sauroleishmania) tarentolae is transmitted by reptile-biting sand flies of the
genus Sergentomyia, but the role of Phlebotomus sand flies in circulation of this parasite is …

[HTML][HTML] Immunotherapeutic Strategies as Potential Treatment Options for Cutaneous Leishmaniasis

A Lafleur, S Daffis, C Mowbray, B Arana - Vaccines, 2024 - mdpi.com
Cutaneous leishmaniasis (CL), caused by protozoan parasites of the Leishmania genus, is
prevalent in tropical and subtropical regions, with important morbidity, particularly in low-to …

[HTML][HTML] Efficacy of mucosal vaccination using a protozoan parasite as a vehicle for antigen delivery: IgG and neutralizing response after rectal administration of …

S Epis, I Varotto-Boccazzi, A Manenti, D Rubolini… - Pharmacological …, 2022 - Elsevier
Mucosal vaccination is regarded as a promising alternative to classical, intramuscular
vaccine delivery. However, only a limited number of vaccines have been licensed for …

Alternative to chemotherapy—The unmet demand against leishmaniasis

N Didwania, M Shadab, A Sabur, N Ali - Frontiers in Immunology, 2017 - frontiersin.org
Leishmaniasis is a neglected protozoan disease that mainly affects the tropical as well as
subtropical countries of the world. The primary option to control the disease still relies on …

Isolation, characterization, and functional study of extracellular vesicles derived from Leishmania tarentolae

M Shokouhy, H Sarvnaz, Y Taslimi… - Frontiers in Cellular …, 2022 - frontiersin.org
Leishmania (L.) species are protozoan parasites with a complex life cycle consisting of a
number of developmental forms that alternate between the sand fly vector and their host …