[HTML][HTML] Mechanism of the gut microbiota colonization resistance and enteric pathogen infection

I Khan, Y Bai, L Zha, N Ullah, H Ullah… - Frontiers in Cellular …, 2021 - frontiersin.org
The mammalian gut microbial community, known as the gut microbiota, comprises trillions of
bacteria, which co-evolved with the host and has an important role in a variety of host …

Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

An integrated gene catalog and over 10,000 metagenome-assembled genomes from the gastrointestinal microbiome of ruminants

F Xie, W Jin, H Si, Y Yuan, Y Tao, J Liu, X Wang… - Microbiome, 2021 - Springer
Background Gastrointestinal tract (GIT) microbiomes in ruminants play major roles in host
health and thus animal production. However, we lack an integrated understanding of …

Interactions between the microbiota and pathogenic bacteria in the gut

AJ Bäumler, V Sperandio - Nature, 2016 - nature.com
The microbiome has an important role in human health. Changes in the microbiota can
confer resistance to or promote infection by pathogenic bacteria. Antibiotics have a profound …

The promise of the gut microbiome as part of individualized treatment strategies

DA Schupack, RAT Mars, DH Voelker… - Nature reviews …, 2022 - nature.com
Variability in disease presentation, progression and treatment response has been a central
challenge in medicine. Although variability in host factors and genetics are important, it has …

[HTML][HTML] Mechanisms of inflammation-driven bacterial dysbiosis in the gut

MY Zeng, N Inohara, G Nuñez - Mucosal immunology, 2017 - Elsevier
The gut microbiota has diverse and essential roles in host metabolism, development of the
immune system and as resistance to pathogen colonization. Perturbations of the gut …

Mitochondria-associated membranes (MAMs) and inflammation

S Missiroli, S Patergnani, N Caroccia, G Pedriali… - Cell death & …, 2018 - nature.com
The endoplasmic reticulum (ER) and mitochondria are tightly associated with very dynamic
platforms termed mitochondria-associated membranes (MAMs). MAMs provide an excellent …

Ethanolamine and phosphatidylethanolamine: partners in health and disease

D Patel, SN Witt - Oxidative medicine and cellular longevity, 2017 - Wiley Online Library
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian
cells. PE comprises about 15–25% of the total lipid in mammalian cells; it is enriched in the …

Vitamin B12 as a modulator of gut microbial ecology

PH Degnan, ME Taga, AL Goodman - Cell metabolism, 2014 - cell.com
The microbial mechanisms and key metabolites that shape the composition of the human
gut microbiota are largely unknown, impeding efforts to manipulate dysbiotic microbial …

Chromatin state dynamics during blood formation

D Lara-Astiaso, A Weiner, E Lorenzo-Vivas, I Zaretsky… - science, 2014 - science.org
Chromatin modifications are crucial for development, yet little is known about their dynamics
during differentiation. Hematopoiesis provides a well-defined model to study chromatin state …