[HTML][HTML] The emerging role of extracellular vesicles in fungi: A double-edged sword

Y Lai, B Jiang, F Hou, X Huang, B Ling, H Lu… - Frontiers in …, 2023 - frontiersin.org
Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

[HTML][HTML] Microbial extracellular vesicles contribute to antimicrobial resistance

B Jiang, Y Lai, W Xiao, T Zhong, F Liu, J Gong… - Plos …, 2024 - journals.plos.org
With the escalating global antimicrobial resistance crisis, there is an urgent need for
innovative strategies against drug-resistant microbes. Accumulating evidence indicates …

Liposomal formulation of a new antifungal hybrid compound provides protection against Candida auris in the ex vivo skin colonization model

A Jaromin, R Zarnowski, A Markowski… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
The newly emerged pathogen, Candida auris, presents a serious threat to public health
worldwide. This multidrug-resistant yeast often colonizes and persists on the skin of patients …

[HTML][HTML] Immunomodulatory potential of fungal extracellular vesicles: Insights for therapeutic applications

S Nenciarini, D Cavalieri - Biomolecules, 2023 - mdpi.com
Extracellular vesicles (EVs) are membranous vesicular organelles that perform a variety of
biological functions including cell communication across different biological kingdoms. EVs …

[HTML][HTML] Extracellular Vesicles from Candida haemulonii var. vulnera Modulate Macrophage Oxidative Burst

BTM Oliveira, TMH Dourado, PWS Santos… - Journal of Fungi, 2023 - mdpi.com
Members of the Candida haemulonii species complex are multidrug-resistant emergent
yeast pathogens able to cause superficial and invasive infections in risk populations. Fungal …

[HTML][HTML] Stress Conditions Affect the Immunomodulatory Potential of Candida albicans Extracellular Vesicles and Their Impact on Cytokine Release by THP-1 Human …

K Kulig, K Bednaruk, E Rudolphi-Szydło… - International Journal of …, 2023 - mdpi.com
Human immune cells possess the ability to react complexly and effectively after contact with
microbial virulence factors, including those transported in cell-derived structures of …

[HTML][HTML] Extracellular vesicle production: A bidirectional effect in the interplay between host and Candida fungi

K Kulig, M Rapala-Kozik, J Karkowska-Kuleta - Current Research in …, 2024 - Elsevier
Candida fungi exploit various virulence strategies to invade the human host, while host cells
employ diverse mechanisms to maintain homeostasis and respond to infection. Extracellular …

[HTML][HTML] Insight into Virulence and Mechanisms of Amphotericin B Resistance in the Candida haemulonii Complex

Y Huang, Y Su, X Chen, M Xiao, Y Xu - Journal of Fungi, 2024 - mdpi.com
The Candida haemulonii complex includes emerging opportunistic human fungal pathogens
with documented multidrug-resistance profiles. It comprises Candida haemulonii sensu …

[HTML][HTML] Fungal extracellular vesicle-mediated regulation: from virulence factor to clinical application

J Liu, X Hu - Frontiers in Microbiology, 2023 - frontiersin.org
Invasive fungal disease (IFD) poses a significant threat to immunocompromised patients and
remains a global challenge due to limited treatment options, high mortality and morbidity …

[HTML][HTML] Fungal Extracellular Vesicles: Isolation, Characterization, and the Immune System Response

MAK Ikeda, RMS Campos, JL Da Silva… - Microbiology …, 2024 - mdpi.com
Like other organisms, fungi produce extracellular vesicles (EVs) that are involved in various
biological processes, including intercellular communication and the transport of molecules …