Increasing evidence links cognitive-decline and Alzheimer's disease (AD) to various sleep
disorders, including obstructive sleep apnea (OSA). With increasing age, there are …

Obstructive sleep apnea syndrome (OSAS), a state of sleep disorder, is characterized by
repetitive apnea, chronic hypoxia, oxygen desaturation, and hypercapnia. Previous studies …

Importance Disrupted sleep is common in aging and is associated with cognition. Age-
related changes to sleep are associated with multiple causes, including early Alzheimer …

Experimental sleep-wake disruption in rodents and humans causally modulates β-amyloid
(Aβ) dynamics (eg,[1–3]). This leads to the hypothesis that, beyond cross-sectional …

There is emerging evidence that obstructive sleep apnea (OSA) is a risk factor for preclinical
Alzheimer's disease (AD). An American Thoracic Society workshop was convened that …

Sleep-disordered breathing is highly prevalent in the elderly population. Obstructive sleep
apnea (OSA) represents the most common sleep disorder among the adult and elderly …

Current theories of the glymphatic system (GS) hypothesize that it relies on cerebrospinal
fluid (CSF) circulation to disseminate growth factors and remove metabolic waste from the …

Here we review the impact of obstructive sleep apnea (OSA) on biomarkers of Alzheimer's
disease (AD) pathogenesis, neuroanatomy, cognition and neurophysiology, and present the …

Background: Sleep disturbance and deficiency are common among older adults and have
been linked with dementia and all-cause mortality. Using nationally representative data, we …

Study Objectives Obstructive sleep apnea (OSA) is accompanied by sleep fragmentation
and altered sleep architecture, which can potentially hinder the glymphatic system …